Staufen 2 regulates mGluR long-term depression and Map1b mRNA distribution in hippocampal neurons [0.03%]
Staufen2调控海马神经元的mGluR长期抑制和Map1b mRNA分布
Geneviève Lebeau,Linda C Miller,Maylis Tartas et al.
Geneviève Lebeau et al.
The two members of the Staufen family of RNA-binding proteins, Stau1 and Stau2, are present in distinct ribonucleoprotein complexes and associate with different mRNAs. Stau1 is required for protein synthesis-dependent long-term potentiation...
The neural cell adhesion molecule-derived peptide FGL facilitates long-term plasticity in the dentate gyrus in vivo [0.03%]
神经细胞粘附分子衍生肽FGL促进体内齿状回的长期可塑性
Glenn Dallérac,Meike Zerwas,Tatiana Novikova et al.
Glenn Dallérac et al.
The neural cell adhesion molecule (NCAM) is known to play a role in developmental and structural processes but also in synaptic plasticity and memory of the adult animal. Recently, FGL, a NCAM mimetic peptide that binds to the Fibroblast Gr...
The role of the hippocampus in retaining relational information across short delays: the importance of memory load [0.03%]
海马在短期延迟内保持关联信息的作用：记忆负荷的重要性
Annette Jeneson,Kristin N Mauldin,Ramona O Hopkins et al.
Annette Jeneson et al.
Patients with hippocampal damage are sometimes impaired at remembering information across delays as short as a few seconds. How are these impairments to be understood? One possibility is that retention of some kinds of information is critic...
Behavioral specifications of reward-associated long-term memory enhancement in humans [0.03%]
人类奖励相关长期记忆增强的行为规范
Bianca C Wittmann,Raymond J Dolan,Emrah Düzel
Bianca C Wittmann
Recent functional imaging studies link reward-related activation of the midbrain substantia nigra-ventral tegmental area (SN/VTA), the site of origin of ascending dopaminergic projections, with improved long-term episodic memory. Here, we i...
Systemic 5-bromo-2-deoxyuridine induces conditioned flavor aversion and c-Fos in the visceral neuraxis [0.03%]
系统性5-溴脱氧尿苷诱导味觉条件反射和c-Fos在内脏神经轴中表达
Adam Kimbrough,Bumsup Kwon,Lisa A Eckel et al.
Adam Kimbrough et al.
5-bromo-2-deoxyuridine (BrdU) is often used in studies of adult neurogenesis and olfactory learning, but it can also have toxic effects on highly proliferative tissue. We found that pairing Kool-Aid flavors with acute systemic injections of...
Odor preference learning and memory modify GluA1 phosphorylation and GluA1 distribution in the neonate rat olfactory bulb: testing the AMPA receptor hypothesis in an appetitive learning model [0.03%]
气味偏好学习记忆改变新生鼠嗅球中GluA1的磷酸化以及采用 appetitive 学习模型验证AMPA受体假说中的GluA1分布
Wen Cui,Andrea Darby-King,Matthew T Grimes et al.
Wen Cui et al.
An increase in synaptic AMPA receptors is hypothesized to mediate learning and memory. AMPA receptor increases have been reported in aversive learning models, although it is not clear if they are seen with memory maintenance. Here we examin...
The tail-elicited tail withdrawal reflex of Aplysia is mediated centrally at tail sensory-motor synapses and exhibits sensitization across multiple temporal domains [0.03%]
海兔尾部反射的中枢介导及多个时间域上的敏感性增强现象
Gary T Philips,Carolyn M Sherff,Steven A Menges et al.
Gary T Philips et al.
The defensive withdrawal reflexes of Aplysia californica have provided powerful behavioral systems for studying the cellular and molecular basis of memory formation. Among these reflexes the tail-elicited tail withdrawal reflex (T-TWR) has ...
Ventral tegmental area and substantia nigra neural correlates of spatial learning [0.03%]
空间学习的中脑黑质和腹侧被盖区神经相关性研究
Adria K Martig,Sheri J Y Mizumori
Adria K Martig
The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) may provide modulatory signals that, respectively, influence hippocampal (HPC)- and striatal-dependent memory. Electrophysiological studies investigating neural corre...
Differential effects of cannabinoid receptor agonist on social discrimination and contextual fear in amygdala and hippocampus [0.03%]
外周给予大麻素受体激动剂对海马和杏仁核介导的社会识别记忆和情境恐惧记忆的影响不同
Amir Segev,Irit Akirav
Amir Segev
We examined whether the cannabinoid receptor agonist WIN55,212-2 (WIN; 5 µg/side) microinjected into the hippocampus or the amygdala would differentially affect memory processes in a neutral vs. an aversive task. In the aversive contextual...
Christopher J Tabone,J Steven de Belle
Christopher J Tabone
Associative conditioning in Drosophila melanogaster has been well documented for several decades. However, most studies report only simple associations of conditioned stimuli (CS, e.g., odor) with unconditioned stimuli (US, e.g., electric s...