Exosomes derived from bone marrow-derived mesenchymal stem cells of exercise-trained mice improve wound healing by inhibiting macrophage M1 polarization [0.03%]
运动小鼠骨髓间充质干细胞源外泌体通过抑制巨噬细胞M1极化促进伤口愈合
Jiling Qiu,Yifan Zhao,Yingyi Chen et al.
Jiling Qiu et al.
Background: Engaging in appropriate exercise is advantageous for our well-being. We investigated whether exercise could affect the paracrine function of BMSCs and whether exosomes derived from treadmill exercise-trained m...
Contribution of cytokeratin 19-expressing cells towards islet regeneration induced by multipotent stromal cell secreted proteins [0.03%]
多能基质细胞分泌蛋白诱导的胰岛再生中表达细胞角蛋白19的细胞的贡献
Nazihah Rasiwala,Gillian I Bell,Anargyros Xenocostas et al.
Nazihah Rasiwala et al.
Residual beta cell function has been documented in 'medalist' patients that have lived with Type 1 diabetes (T1D) for >50 years. In addition, endocrine cell neogenesis first occurs in the developing human embryo from a progenitor cells deri...
Neural stem cell-derived extracellular vesicles alleviate inflammatory responses in a mouse model of atopic dermatitis [0.03%]
神经干细胞源外泌体通过作用于巨噬细胞减轻小鼠AD炎症反应
Seulbee Lee,Donghun Hyun,Yong Namkung et al.
Seulbee Lee et al.
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by disrupted epidermal barrier function and excessive immune activation. Conventional treatments using corticosteroids and immunosuppressants provide only temporar...
Transcriptomic Analysis of the m6A Reader YTHDF2 in the Maintenance and Differentiation of Human Embryonic Stem Cells [0.03%]
YTHDF2（m6A读取蛋白）在人胚胎干细胞维持和分化中的转录组分析
Boshi Feng,Yanxi Chen,Huanchang Tu et al.
Boshi Feng et al.
As the most abundant internal modification on mRNAs, N6-methyladenosine (m6A) has been discovered to be involved in different biological processes. Mostly determined by m6A methyl-transferases (m6A writers) and demethylases (m6A erasers), d...
Stem cell CNTF promotes olfactory epithelial neuroregeneration and functional recovery following injury [0.03%]
神经干细胞分泌的CNTF促进损伤后嗅觉上皮神经再生及功能恢复
Derek Cox,Brian Wang,Joe Oliver et al.
Derek Cox et al.
Olfactory sensory neurons (OSNs) in the olfactory epithelium (OE) are continuously replaced by neuroregeneration from basal stem cells. Acute inflammation destroys OSNs, causing hyposmia or anosmia, but leaves the basal stem cells intact. W...
Rabbit Induced Pluripotent Stem Cells -Derived Mesenchymal Stem Cells for Enhanced Wound Healing [0.03%]
兔诱导多能干细胞来源的间充质干细胞促进伤口愈合
Hsing-Yi Yu,Yang-Zhe Huang,Edward Chern
Hsing-Yi Yu
Mesenchymal stem cells (MSCs) are pivotal in regenerative medicine, particularly for their efficacy in tissue repair. However, sourcing high-quality MSCs presents challenges due to limited availability and compromised function. Induced plur...
In Reply to Letter to the Editor from Paudel: Comment on "Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers" [0.03%]
对Paudel读者来信的回复：“iPSC-星形胶质细胞形态变化反映阿尔茨海默病患者临床标志物”的评论
Noel J Buckley,Helen A Rowland
Noel J Buckley
Stem Cells and Female Reproduction: Endometrial Physiology, Disease and Therapy [0.03%]
干细胞与女性生殖：子宫内膜生理、疾病及治疗
E Cansu Cevik,Ramanaiah Mamillapalli,Hugh S Taylor
E Cansu Cevik
The human endometrium, a dynamic tissue that undergoes cyclical shedding, repair, regeneration, and remodeling, relies on progenitor stem cells for replenishment. Bone marrow-derived mesenchymal stem cells (BM-MSCs) also may play a crucial ...
E3 ligase Trim63 promotes the chondrogenic differentiation of mesenchymal stem cells by catalyzing K27-linked cysteine ubiquitination of Myh11 [0.03%]
E3连接酶Trim63通过催化Myh11的K27链型半胱氨酸泛素化促进间充质干细胞向软骨细胞分化
Shanyu Ye,Yanqing Wang,Ziwei Luo et al.
Shanyu Ye et al.
Mesenchymal stem cells (MSCs) are multipotent stem cells that have a chondrogenic differentiation capacity. However, the molecular mechanism underlying the chondrogenic differentiation of MSCs has not been fully elucidated, which hinders fu...