Stem cell therapy for osteoradionecrosis of the jaws: Mechanisms, advances, and clinical potential [0.03%]
牙源性放射性坏死的干细胞治疗：机制、进展与临床潜力
Haiou Liu,Ran Nie,Jinlan Jiang et al.
Haiou Liu et al.
Osteoradionecrosis of the jaws (ORNJ) is a severe aseptic complication of high-dose radiotherapy for head-and-neck cancers, characterized by chronic jawbone necrosis, functional impairment, and poor responses to traditional treatments (e.g....
Critical Insights into Umbilical Cord Blood and Tissue Stem Cells: Navigating Challenges to Enhance Clinical Translation - A Narrative Review [0.03%]
脐带血和组织干细胞的批判性见解：克服挑战以增强临床转化- 一篇叙述性综述
Kosar Fateh,Amir Atashi
Kosar Fateh
Background: Umbilical cord blood (UCB) and umbilical cord tissue (UCT) are non-invasive, readily available sources of stem cells with significant potential for regenerative medicine and hematopoietic transplantation. Whil...
Stem cell specification and niche formation in developing incisor requires actomyosin forces [0.03%]
牙釉质发育过程中干细胞的指定和小生境形成需要肌动蛋白-myosin力的作用
Yasmin Mohtadi Hamadani,Laura Evers,Satu-Marja Myllymaki et al.
Yasmin Mohtadi Hamadani et al.
The precise timing of stem cell specification and niche formation during murine incisor development is poorly understood, and it is unclear whether these processes occur simultaneously or in a sequential manner. Functional dental epithelial...
Macrophage Heterogeneity and Plasticity in Liver Injury and Repair Mechanisms [0.03%]
肝损伤和修复机制中的巨噬细胞异质性和可塑性
Tianjiao Zhang,Paul Horn,Moritz Peiseler et al.
Tianjiao Zhang et al.
Hepatic macrophages, encompassing embryonic Kupffer cells (emKCs) and monocyte-derived macrophages (MoMFs), are recognized as important regulators of hepatic homeostasis and key players in the pathogenesis of liver diseases such as metaboli...
Opportunities with artificial intelligence in assessing the potency of mesenchymal stromal cells [0.03%]
人工智能在间充质基质细胞效力评估中的机遇
Raghavan Chinnadurai,Anant Madabhushi
Raghavan Chinnadurai
Determining the potency of MSCs is a critical component of their application as cellular therapies. The function of MSCs does not rely on a single mechanism but rather on overlapping and cumulative effector pathways, which necessitates the ...
Mesenchymal stromal cell therapy for scarring: a systematic review of clinical and preclinical studies [0.03%]
间充质基质细胞治疗疤痕：临床和前期研究的系统性回顾
Laura Hansen,Cecilie Mullerup Laustsen-Kiel,Filip Rangatchew et al.
Laura Hansen et al.
Background: Mesenchymal stromal/stem cell (MSC) transplantation has emerged as a promising therapeutic strategy for managing cutaneous scarring, an issue associated with significant aesthetic and functional morbidity. Thi...
Age-associated T cell immunity decreases circulating endothelial progenitor cells [0.03%]
年龄相关的T细胞免疫降低循环中的内皮祖细胞数量
Fang Zhang,Qiuchen Zhao,Shuzhen Guo et al.
Fang Zhang et al.
A reduction in circulating endothelial progenitor cells (EPCs) comprise an important part of vascular aging. However, the underlying mechanisms that mediate this EPC decline remain unclear. Here, we demonstrate a novel molecular mechanism w...
Bovine Formative Embryonic Stem Cell Plasticity in Embryonic and Extraembryonic Differentiation [0.03%]
牛源表始期胚胎干细胞分化多潜能性研究
Yue Su,Ruifeng Zhao,Yifei Fang et al.
Yue Su et al.
Bovine embryonic stem cells (bESCs) can greatly enhance the understanding of bovine embryonic development and applications for disease-resistance, biomedical and zoonotic pre-clinical models. However, formative bESCs with distinct morpholog...