Let her shine: Empowering women and closing India's gender gap in STEM [0.03%]
让女性大放异彩：赋力印度STEM领域妇女及弥合性别差距
Aparajita Chattopadhyay
Aparajita Chattopadhyay
Despite globally increasing numbers of women in the STEM workforce, levels still remain suboptimal. Closing the gender gap in an emerging economic power such as India, requires a cultural shift, active support of girls' education, and more ...
Acceptability and safety of one versus three months of rifapentine and isoniazid to prevent tuberculosis in people exposed in the household or workplace in Brazil: The Ultra-Curto randomized controlled trial [0.03%]
巴西家户或工作场所暴露人群使用利福平和异烟肼1个月与3个月预防结核病的可接受性和安全性：Ultra-Curto随机对照试验
Betina Durovni,Marcelo Cordeiro-Santos,Solange Cesar Cavalcante et al.
Betina Durovni et al.
Background: Short-course tuberculosis preventive therapy with isoniazid and rifapentine (HP) is widely recommended, but the acceptability and safety of one month of daily HP (1HP) compared to three months of weekly HP (3H...
Clinical Trial
PLoS medicine. 2026 Feb 10;23(2):e1004758. DOI:10.1371/journal.pmed.1004758 2026
The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts [0.03%]
柳叶刀肥胖委员会关于肥胖的定义对东亚人群流行率及其长期心肾代谢预后的影响：社区队列研究
David T W Lui,Carol H Y Fong,Xincheng Zou et al.
David T W Lui et al.
Background: The Lancet Commission proposed an update in January 2025 on the definition of obesity which requires at least one anthropometric measurement in addition to body mass index (BMI) to confirm excess adiposity. Al...
Observational Study
PLoS medicine. 2026 Feb 9;23(2):e1004749. DOI:10.1371/journal.pmed.1004749 2026
Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption [0.03%]
螺内酯增效剂在高血压治疗中的突破与应用障碍
Luke J Laffin,Steven E Nissen
Luke J Laffin
Despite many antihypertensive options, uncontrolled hypertension remains pervasive. Aldosterone synthase inhibitors show robust blood pressure reductions and have the potential to reshape hypertension treatment, though cost and access may i...
Jack Le Vance,Matthew Vaughan,Tanvi Bhatia et al.
Jack Le Vance et al.
Background: Ultrasound is a common diagnostic modality in obstetrics to evaluate the fetal condition, frequently used in pregnant women classifying as high-risk. Modifications to guidelines, implementation of national ini...
Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study [0.03%]
估算可行结核分枝杆菌感染的全球疾病负担：数学模型研究
Alvaro Schwalb,Peter J Dodd,Hannah M Rickman et al.
Alvaro Schwalb et al.
Background: Estimating the proportion of individuals currently infected with Mycobacterium tuberculosis (Mtb) is key for informing global health policies. Although a substantial portion of the global population exhibit tu...
Targeting spinal cord perfusion pressure in acute spinal cord injury through cerebrospinal fluid drainage: A prospective multi-center clinical trial [0.03%]
腰椎穿刺脑脊液引流调控急性脊髓损伤患者脊髓灌注压的前瞻性多中心临床研究
Cameron M Gee,Angela Tsang,Miko McKenzie et al.
Cameron M Gee et al.
Background: The hemodynamic management of acute spinal cord injury (SCI) aims to improve perfusion and mitigate ischemic secondary injury to the injured spinal cord, traditionally through the augmentation of mean arterial...
Clinical Trial
PLoS medicine. 2026 Feb 5;23(2):e1004925. DOI:10.1371/journal.pmed.1004925 2026
Mother and child health 4.5 years after gestational diabetes mellitus managed using tight or less tight targets for glycaemic control: Post-hoc follow-up study of the TARGET trial [0.03%]
妊娠糖尿病患者采用严格或不太严格的血糖控制标准对母婴健康的影响：TARGET试验的事后随访研究
Lisa J Douglas,Greg D Gamble,Jane E Harding et al.
Lisa J Douglas et al.
Background: Optimal glycaemic targets for women with gestational diabetes mellitus (GDM) are unclear. The aim of this study was to compare maternal and child health 4.5 years after women with GDM had been randomised to us...
Randomized Controlled Trial
PLoS medicine. 2026 Feb 3;23(2):e1004635. DOI:10.1371/journal.pmed.1004635 2026
The mpox epidemic is not over: Reducing disproportionate burden in Africa and persistent global risk require a sustained response [0.03%]
猴痘疫情尚未结束：减轻非洲的不成比例负担和应对持续存在的全球风险需要持续响应
Dieudonné Mwamba Kazadi,Rosamund F Lewis,Pierre Akilimali et al.
Dieudonné Mwamba Kazadi et al.
While global interest in mpox may be waning, outbreaks, illness, and death continue across Africa and the world. Ending transmission requires a sustained global response that moves beyond reactive measures. ...
Social inequalities in patient outcomes after total hip replacement surgery for osteoarthritis in England: A population-based cohort study of the National Joint Registry [0.03%]
基于国家关节登记册的全髋关节置换术患者的结局的社会差异：队列研究
Rita Patel,Erik Lenguerrand,Yoav Ben-Shlomo et al.
Rita Patel et al.
Background: Reducing health inequalities is of national importance. Total hip replacement (THR) is a commonly used elective surgical procedure. Few studies have examined area-level inequalities for a wide range of outcome...