The data transparency crisis in research: Lessons from systematic reviews and meta-analyses [0.03%]
研究中的数据透明度危机：系统评价和-meta-分析的启示
Saul Martin-Rodriguez,Rodrigo Fernandez-Gonzalo,David Moher
Saul Martin-Rodriguez
Systematic reviews and meta-analyses underpin clinical guidelines and health policy, yet their validity may be compromised by limited access to underlying datasets and associated analytical code.Reliance on incomplete or inconsistently repo...
Comparison of count-based and clustering definitions of multimorbidity and their association with prevalence of multimorbidity, health profiles, and mortality: A cohort study of UK Biobank participants [0.03%]
基于计数和聚类的多重疾病的定义及其与多重疾病患病率、健康状况及死亡率关联性的对比研究：一项关于英国生物银行队列的研究
Gabriella C Silva,Aurore Fayosse,Louis Jacob et al.
Gabriella C Silva et al.
Background: Multimorbidity, the presence of several chronic conditions, is linked to higher mortality and healthcare use and thus poses a major challenge for aging populations. While most studies rely on simple counts of ...
Placenta accreta spectrum in the 21st century: Challenging dogma and redefining disorder [0.03%]
二十一世纪的胎盘粘连谱系：挑战传统观念和重新定义疾病
Eric Jauniaux,Helena C Bartels,Yalda Afshar
Eric Jauniaux
Placenta accreta spectrum (PAS) is a serious pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux and colleagues discuss emerging evidence that challenges our long-held pathophysio...
Prediction of hospitalisation in young children with pneumonia in Malawi: A machine learning-based approach [0.03%]
基于机器学习的马拉维肺炎患儿住院率预测模型研究
Patrick Staunton,Mohammad Adib Makrooni,Master Chisale et al.
Patrick Staunton et al.
Background: Globally, pneumonia remains the single biggest cause of mortality in children under 5 years of age. This study sought to train and test a prediction model for hospitalisation within 7 days after initial presen...
Molecular Tumor Boards clinical impact on patient care and structural features: A systematic review and meta-analysis [0.03%]
分子肿瘤委员会对患者护理的临床影响及其结构特征的系统评价和meta分析
Luigi Russo,Erika Giacobini,Nicolò Lentini et al.
Luigi Russo et al.
Background: Molecular Tumor Boards (MTBs) bring together multidisciplinary experts to translate genomic data into clinical decisions in oncology, however, their overall clinical impact remains unclear. The aim of this sys...
Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy [0.03%]
超越关联：探讨非甾体抗炎药（NSAIDs）在早期妊娠中的安全性导航
Andrew S C Yuen,Kenneth K C Man
Andrew S C Yuen
Pain and fever in pregnancy require treatment, but fetal safety concerns complicate analgesic choice. A recent PLOS Medicine study presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but interp...
Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study [0.03%]
巴西、哥伦比亚和秘鲁监狱系统结核病筛查策略的影响与成本效益分析：数学建模研究
Yiran E Liu,José Victor Bortolotto Bampi,Ronan F Arthur et al.
Yiran E Liu et al.
Background: Incarceration is a leading driver of tuberculosis in Latin America. Systematic screening in prisons may reduce tuberculosis burden, but optimal strategies and cost-effectiveness remain uncertain. We examined t...
Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis [0.03%]
无症状单胎妊娠妇女宫颈长度对自发性早产的预测价值：个体患者数据分析的meta分析
Kelly Hughes,David Nguyen,Mason Aberoumand et al.
Kelly Hughes et al.
Background: Spontaneous preterm birth (SPTB) is the leading cause of perinatal and early childhood mortality worldwide. Studies have generally suggested that mid-trimester transvaginal sonographic cervical length
Meta-Analysis
PLoS medicine. 2026 Jun 2;23(6):e1004653. DOI:10.1371/journal.pmed.1004653 2026
Proteomic signatures of early retinal neurodegeneration in type 2 diabetes mellitus [0.03%]
2型糖尿病视网膜早期神经退行性变的蛋白质组学标志物研究
Huangdong Li,Ziyu Zhu,Shaopeng Yang et al.
Huangdong Li et al.
Background: Retinal neurodegeneration is an early and independent feature of diabetic retinal disease and has been proposed as a window into the systemic neural consequences of diabetes, yet accessible molecular biomarker...
Observational Study
PLoS medicine. 2026 Jun 2;23(6):e1004868. DOI:10.1371/journal.pmed.1004868 2026
Prenatal exposure to asthma medications and risk of neurodevelopmental disorders and educational difficulties: A systematic review and meta-analysis [0.03%]
孕期接触哮喘药物与神经发育障碍和学习困难风险的相关性：系统回顾和荟萃分析
Lama A Shakhshir,Alexia Karain,Jill P Pell et al.
Lama A Shakhshir et al.
Background: Since asthma exacerbations during pregnancy risk maternal and fetal health, continued medication is important. However, some studies have reported adverse neurodevelopmental outcomes following prenatal exposur...
Meta-Analysis
PLoS medicine. 2026 Jun 1;23(6):e1005100. DOI:10.1371/journal.pmed.1005100 2026