Pregnancy outcomes in women at high risk of preterm birth receiving a vaginal cervical cerclage with, or without, progesterone: A retrospective, secondary analysis of the C-STICH randomised controlled trial data [0.03%]
宫颈环扎术联合或不联合孕酮对预防预产期前分娩的孕妇的效果:来自C-STITCH随机对照试验的回顾性、二次分析数据
Victoria Hodgetts Morton,R Katie Morris,Philip Toozs-Hobson et al.
Victoria Hodgetts Morton et al.
Background: Vaginal cervical cerclage and progesterone are established treatments for prevention of pregnancy loss and prematurity. There is limited data to assess the effect of these treatments in combination. The object...
Correction: Sex-specific associations of adiposity with cardiometabolic traits in the UK: A multi-life stage cohort study with repeat metabolomics [0.03%]
纠正:在英国多生命周期队列研究中重复代谢组学与心血管代谢特征的性别差异关联性分析
Linda M OKeeffe,Joshua A Bell,Kate N ONeill et al.
Linda M OKeeffe et al.
[This corrects the article DOI: 10.1371/journal.pmed.1003636.]. Copyright: © 2026 O’Keeffe et al. This is an open access article distributed under the ...
Published Erratum
PLoS medicine. 2026 Jan 23;23(1):e1004901. DOI:10.1371/journal.pmed.1004901 2026
Psychological distress among Japanese high school students during the COVID-19 pandemic: An energy landscape analysis [0.03%]
新冠肺炎疫情期间日本高中生的心理压力:能量景观分析
Daiki Tatematsu,Naotoshi Nakamura,Masato S Abe et al.
Daiki Tatematsu et al.
Background: The stay-at-home orders, lockdowns, and states of emergency of the Coronavirus Infectious Disease emerged in 2019 (COVID-19) pandemic have affected the mental health of school-aged children. Previous reports o...
The benefits and risks of maternal RSV vaccination on mortality in South Africa: A modeling study [0.03%]
南非母体RSV免疫对婴儿死亡率的影响:基于模型的研究
Ayaka Monoi,Akira Endo,Simon R Procter et al.
Ayaka Monoi et al.
Background: Maternal respiratory syncytial virus (RSV) vaccine, RSV prefusion F protein vaccine (RSVpreF (Abrysvo)), was found to be safe and efficacious in the MATISSE trial. However, post-hoc stratified analyses identif...
Missing tissue, missing data: Resolving brain volume loss caused by anti-amyloid therapies [0.03%]
缺失的组织,缺失的数据:解决抗淀粉样蛋白治疗引起的脑体积损失问题
Francesca Alves,Scott Ayton
Francesca Alves
Anti-amyloid drugs modestly slow Alzheimer's disease progression, albeit with uncertainty of sustained benefit, particularly as they cause paradoxical acceleration of brain volume changes. Here, we examine explanations for these volume chan...
Glucagon-like peptide-1 receptor agonists for obesity: Growing popularity met with growing questions over safety [0.03%]
GLP-1受体激动剂治疗肥胖:日益流行的药物伴随着安全性的争议增加
Ariana M Chao,Adam Gilden,Thomas A Wadden
Ariana M Chao
Glucagon-like peptide-1 (GLP-1)-based medications, such as semaglutide and tirzepatide, have transformed obesity care. However, rising use brings concerns about side effects, long-term outcomes, and unregulated products. Ensuring safe acces...
Multiview deep-learning-enabled histopathology for prognostic and therapeutic stratification in stage II colorectal cancer: A retrospective multicenter study [0.03%]
基于多视图深度学习的II期结直肠癌预后及治疗分层组别的组织病理学研究:一项回顾性多中心研究
Zihan Zhao,Dexia Chen,Ruixuan Wang et al.
Zihan Zhao et al.
Background: Approximately 20% of patients with stage II colorectal cancer (CRC) experience tumor relapse despite standard surgical treatment. Histopathological analysis holds promise for postsurgical risk stratification a...
Multicenter Study
PLoS medicine. 2026 Jan 13;23(1):e1004614. DOI:10.1371/journal.pmed.1004614 2026
Evaluating the clinical utility of large language models for hepatocellular carcinoma treatment recommendations: A nationwide retrospective registry study [0.03%]
评估大型语言模型在肝细胞癌治疗建议中的临床实用性:一项全国性回顾性登记研究
Keungmo Yang,Jaejun Lee,Jeong Won Jang et al.
Keungmo Yang et al.
Background: Hepatocellular carcinoma (HCC) management requires complex decision-making considering tumor burden, liver function, and patient's functional performance status. Large language models (LLMs) show promise in cl...
Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: A meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage [0.03%]
非洲和南亚肺炎克雷伯菌新生儿败血症中荚膜和O型的分布:基因组预测血清型流行率的meta分析,以期为潜在疫苗覆盖率提供信息
Thomas D Stanton,Shaun P Keegan,Jabir A Abdulahi et al.
Thomas D Stanton et al.
Background: Klebsiella pneumoniae causes ~20% of sepsis in neonates, with ~40% crude mortality. A vaccine administered to pregnant women, protecting against ≥70% of K. pneumoniae infections, could avert ~400,000 cases an...
Public health impacts of increasing the minimum unit price for alcohol in Scotland: A model-based appraisal [0.03%]
提高苏格兰酒精最低限价对公共健康的影响:基于模型的评估
John Holmes,Damon Morris,Duncan Gillespie et al.
John Holmes et al.
Background: Governments in several countries have introduced a minimum unit price (MUP) for alcohol. Evaluation studies suggest this has reduced alcohol-related harm, but MUPs must increase with inflation to remain effect...