The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study [0.03%]
国际捐助资金减少对低收入和中等收入国家结核病家庭经济负担潜在影响的模型研究
Allison Portnoy,Rebecca A Clark,Mark Jit et al.
Allison Portnoy et al.
Background: Recent shifts in the global health funding landscape-most notably the dismantling of the United States Agency for International Development (USAID) and possible reduced contributions to the Global Fund to Figh...
Health disparities in transitions between kidney replacement therapy modalities and mortality in England: A multistate model using UK Renal Registry data [0.03%]
英国肾脏登记处资料的多状态模型分析了英格兰地区肾替代治疗转换与死亡率之间的差距
Jessica Potts,Camille M Pearse,Mark Lambie et al.
Jessica Potts et al.
Background: While ethnic and deprivation-related disparities in kidney replacement therapy (KRT) initiation are well established, their impact on transitions between treatment modalities and mortality over the course of k...
Can generative artificial intelligence enhance evidence-based and personalized medicine? [0.03%]
生成式人工智能能否增强循证和个性化医疗？
Arun J Thirunavukarasu
Arun J Thirunavukarasu
Should clinical applications of generative artificial intelligence (GAI) be designed to follow treatment guidelines rigidly, provide individualized recommendations, or be somewhere in-between? A recent study in PLOS Medicine comparing GAI v...
The effect of prenatal balanced energy and protein supplementation on small vulnerable newborn types in low- and middle-income countries: A systematic review and meta-analysis of individual participant data [0.03%]
孕期均衡能量和蛋白质补充对低收入和中等收入国家易感新生儿的影响：个体患者数据分析的系统评价和meta分析
Dongqing Wang,Uttara Partap,Enju Liu et al.
Dongqing Wang et al.
Background: Small vulnerable newborn (SVN) types, defined by combinations of being born too soon or too small, have distinct determinants, health consequences, and prevention strategies. The effects of prenatal balanced e...
Meta-Analysis
PLoS medicine. 2026 Feb 17;23(2):e1004716. DOI:10.1371/journal.pmed.1004716 2026
The role of comorbidities in the associations between air pollution and Alzheimer's disease: A national cohort study in the American Medicare population [0.03%]
合并症在空气污染与阿尔茨海默病关联中的作用：美国Medicare人口全国队列研究
Yanling Deng,Yang Liu,Hua Hao et al.
Yanling Deng et al.
Background: Air pollution and several common comorbidities-such as hypertension, stroke, and depression-are established risk factors for Alzheimer's disease (AD). However, whether these comorbidities mediate or amplify th...
Eliminating ghost workers and optimizing resources to strengthen Community Health Worker programs in sub-Saharan Africa [0.03%]
消除虚假员工并优化资源以加强撒哈拉以南非洲的社区卫生工作者项目
Temesgen Ayehu,Josiah F Joekai Jr,Mulbah K Yorgbor et al.
Temesgen Ayehu et al.
Although community health workers (CHWs) play a vital role in filling health workforce gaps, they remain inadequately compensated due to insufficient domestic financing. In this Policy Forum article, Temesgen Ayehu and colleagues discuss ho...
Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study [0.03%]
基于新结核病疫苗针对具有传染性的无症状结核病疗效的群体影响估计：一项建模研究
Hira Tanvir,Rebecca A Clark,Tom Sumner et al.
Hira Tanvir et al.
Background: Tuberculosis (TB) remains a leading cause of infectious disease death. New TB vaccines are currently in late-stage trials and may be available before the end of the decade. Modelling predicts new TB vaccines m...
Evaluation of rotavirus, pneumococcal conjugate and human papillomavirus vaccination in four Pacific island countries: A cost-effectiveness modelling study [0.03%]
四种太平洋岛国轮状病毒、肺炎球菌结合疫苗和人乳头瘤病毒疫苗效果评价的成本效益模型研究
Natalie Carvalho,Emma Watts,Victoria L Oliver et al.
Natalie Carvalho et al.
Background: The introduction of rotavirus vaccine (RVV), pneumococcal conjugate vaccine (PCV) and human papillomavirus vaccine (HPVV) has been slow in Pacific Island Countries, particularly among middle-income countries. ...
Associations of Creatinine Muscle Index with markers of sarcopenia and mortality in chronic kidney disease: A prospective cohort study [0.03%]
慢性肾脏疾病患者血清肌酐肌肉指数与低肌肉量、虚弱和全因死亡率的关系：前瞻性队列研究
Thomas McDonnell,Thomas Phillips,Philip A Kalra et al.
Thomas McDonnell et al.
Background: Sarcopenia is common in chronic kidney disease (CKD) and linked to higher mortality, but identifying those at risk remains challenging. Indices combining serum creatinine and cystatin C (eGFRratio and eGFRdiff...
Multicenter Study
PLoS medicine. 2026 Feb 12;23(2):e1004775. DOI:10.1371/journal.pmed.1004775 2026
Systematic assessment of obesity-related risk factors in renal cancer etiology: A longitudinal risk and mendelian randomization analysis [0.03%]
系统评估肥胖相关风险因素在肾癌病因学中的作用：一项纵向风险和孟德尔随机化分析
Karine Alcala,Daniela Mariosa,Sara Jacobson et al.
Karine Alcala et al.
Background: Excess body adiposity is an established cause of renal cancer, but underlying molecular pathways mediating this relationship remain unclear. This study aimed to systematically evaluate a panel of obesity-relat...