Yuuta Imoto,Shigeki Watanabe
Yuuta Imoto
Endocytosis in non-neuronal cells requires gradual recruitment of proteins to endocytic sites for inducing membrane curvature and forming contractile scaffolds around the neck of endocytic pits. This recruitment process is thought to be rat...
Undernutrition-Associated Diabetes Mellitus: Pathophysiology of a Global Problem [0.03%]
与营养不良有关的糖尿病：全球性问题的病理生理学分析
Pradnyashree Wadivkar,Nihal Thomas,Felix Jebasingh et al.
Pradnyashree Wadivkar et al.
Early-life undernutrition is known to be a potentially important risk factor for the development of diabetes mellitus in adult life. Additionally, some literature suggests that undernutrition during later life or adulthood may lead to metab...
Yi-Hsuan Chiang,Stephan Emmrich,Nicola Vannini
Yi-Hsuan Chiang
Aging is a multifaceted process associated with a functional decline in cellular function over time, affecting all lifeforms. During the aging process, metabolism, a fundamental hallmark of life (1), is profoundly altered. In the context of...
Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome [0.03%]
肌痛性脑脊髓炎/慢性疲劳综合征中的线粒体功能障碍
Abu Mohammad Syed,Alexander K Karius,Jin Ma et al.
Abu Mohammad Syed et al.
ME/CFS is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms is prolonged fatigue following exertion, a feature also observed in long COVID, suggesting an underlying...
Synthetic forms most beautiful: engineering insights into self-organization [0.03%]
仿生结构最美丽：论自组织的工程学观点
Zhejing Xu,Chih-Chia Chang,Scott Coyle
Zhejing Xu
Reflecting on the diversity of the natural world, Darwin famously observed that "from so simple a beginning endless forms most beautiful and most wonderful have been, and are being evolved". However, the examples that we are able to observe...
Mark A Knepper
Mark A Knepper
Over the past several decades, physiological research has undergone a progressive shift toward greater-and-greater reductionism, culminating in the rise of 'molecular physiology.' The introduction of Omic techniques, chiefly protein mass sp...
Li Cheng,Jielin Li,Yaojun Chen et al.
Li Cheng et al.
Genomic rearrangements play an important role in shaping genetic diversity, as they enable the generation of novel structural variations through specific genome manipulation tools. These variations contribute to phenotypic differences among...
Yufan Feng,Huixian Qiu,Danica Chen
Yufan Feng
Xinyue Chen,Yueqing Peng,X Shawn Liu
Xinyue Chen
Understanding neural mechanisms of memory has been one of the key questions in biology. Long-term memory specifically, allows one to travel mentally without constraints of time and space (1). A long-term memory must have gone through a seri...
Yuki Sato
Yuki Sato
As life expectancy increases globally, the prevalence and severity of age-related disease has risen, significantly impacting patients' quality of life and increasing dependency on the health care system. Age-related diseases share several p...