Friedrich C Luft
Friedrich C Luft
Stimulating antibodies against G-protein-coupled receptors, including the β1- and β2-adrenergic receptors, the α1-adrenergic receptor, and the angiotensin II AT1 receptor, have been described, as well as activating antibodies directed at...
Alfonso Eirin,Lilach O Lerman
Alfonso Eirin
Renal artery stenosis remains an important contributor to renal failure in the elderly population, but uncertainty continues to surround the mechanisms underlying progressive renal dysfunction. Here, we present the current understanding of ...
Margaret A Zimmerman,Jennifer C Sullivan
Margaret A Zimmerman
Hypertension is a complex and multifaceted disease, and there are well established sex differences in many aspects of blood pressure (BP) control. The intent of this review is to highlight recent work examining sex differences in the molecu...
Babbette LaMarca,Denise Cornelius,Kedra Wallace
Babbette LaMarca
Preeclampsia is associated with hypertension and increased infant and maternal morbidity and mortality. The underlying cause of preeclampsia is largely unknown, but it is clear that an immunological component plays a key pathophysiological ...
Role of β-adrenergic receptors and nitric oxide signaling in exercise-mediated cardioprotection [0.03%]
β肾上腺素受体和一氧化氮信号在运动介导的心脏保护中的作用
John W Calvert,David J Lefer
John W Calvert
Exercise promotes cardioprotection in both humans and animals not only by reducing risk factors associated with cardiovascular disease but by reducing myocardial infarction and improving survival following ischemia. This article will define...
Gary C Sieck,Carlos Mantilla,Merryn Tawhai
Gary C Sieck
Gary C Sieck,Yasser El-Wazir,Nelson Escobales et al.
Gary C Sieck et al.
cAMP and mitochondria [0.03%]
环磷腺苷和线粒体
Federica Valsecchi,Lavoisier S Ramos-Espiritu,Jochen Buck et al.
Federica Valsecchi et al.
Phosphorylation of mitochondrial proteins has emerged as a major regulatory mechanism for metabolic adaptation. cAMP signaling and PKA phosphorylation of mitochondrial proteins have just started to be investigated, and the presence of cAMP-...
Gap junction remodeling in skin repair following wounding and disease [0.03%]
创伤和疾病后皮肤修复过程中的连接蛋白通道重塑机制研究
Jared M Churko,Dale W Laird
Jared M Churko
In the present review, we provide an overview of connexin expression during skin development and remodeling in wound healing, and reflect on how loss- or gain-of-function connexin mutations may change cellular phenotypes and lead to disease...