Mechanism and physiological significance of growth factor-related autophagy [0.03%]
生长因子诱导的自噬的发生机制及其生理意义研究进展
Terytty Yang Li,Shu-Yong Lin,Sheng-Cai Lin
Terytty Yang Li
Growth factors, typically defined as natural substances capable of stimulating cell growth and differentiation, are vital regulators for the survival of metazoan cells. In this review, we will focus on growth factor signaling pathways that ...
Robert S Rogers,Jahar Bhattacharya
Robert S Rogers
More than 40 variations of intercellular organelle transfer, such as a mitochondria or lysosome originating in one cell being transported to another cell, have been described. We review the mechanisms and subcellular structures by which, an...
Béla Suki,Susumu Sato,Harikrishnan Parameswaran et al.
Béla Suki et al.
Transpulmonary pressure and the mechanical stresses of breathing modulate many essential cell functions in the lung via mechanotransduction. We review how mechanical factors could influence the pathogenesis of emphysema. Although the progre...
Matrix metalloproteinase-9: Many shades of function in cardiovascular disease [0.03%]
心血管疾病中基质金属蛋白酶-9的多种功能状态
Andriy Yabluchanskiy,Yonggang Ma,Rugmani Padmanabhan Iyer et al.
Andriy Yabluchanskiy et al.
Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates pathological remodeling processes that involve inflammation and fibrosis in cardiovascular disease. MMP-9 directly degrades extracellular matrix (ECM) pro...
Daniel J Tschumperlin
Daniel J Tschumperlin
Fibroblast migration is essential to normal wound healing and pathological matrix deposition in fibrosis. This review summarizes our understanding of how fibroblasts navigate 2D and 3D extracellular matrices, how this behavior is influenced...
Sri Ram Krishna Vedula,Andrea Ravasio,Chwee Teck Lim et al.
Sri Ram Krishna Vedula et al.
Collective cell migration is fundamental to gaining insights into various important biological processes such as wound healing and cancer metastasis. In particular, recent in vitro studies and in silico simulations suggest that mechanics ca...
Gary Sieck
Gary Sieck
Rolf D Hubmayr
Rolf D Hubmayr
Gary C Sieck,Peter Hunter,Jeffrey Fredberg et al.
Gary C Sieck et al.
Susan M Barman,Kim E Barrett,David Pollock
Susan M Barman