Bastiaan C Du Pré,Toon A B Van Veen,Martin E Young et al.
Bastiaan C Du Pré et al.
Circadian rhythms are of major importance in mammalian physiology and disease. In this review, we give an overview of the present knowledge on origination of circadian rhythms. We discuss the development of both master and peripheral clocks...
Diethelm W Richter,Jeffrey C Smith
Diethelm W Richter
The cellular and circuit mechanisms generating the rhythm of breathing in mammals have been under intense investigation for decades. Here, we try to integrate the key discoveries into an updated description of the basic neural processes gen...
Gasotransmitter regulation of ion channels: a key step in O2 sensing by the carotid body [0.03%]
一氧化氮等气体信号分子对离子通道的调节作用是颈动脉体氧感受的关键步骤
Nanduri R Prabhakar,Chris Peers
Nanduri R Prabhakar
Carotid bodies detect hypoxia in arterial blood, translating this stimulus into physiological responses via the CNS. It is long established that ion channels are critical to this process. More recent evidence indicates that gasotransmitters...
Unexpected benefits of intermittent hypoxia: enhanced respiratory and nonrespiratory motor function [0.03%]
间断性缺氧的意外益处：增强呼吸和非呼吸运动功能
E A Dale,F Ben Mabrouk,G S Mitchell
E A Dale
Intermittent hypoxia (IH) is most often thought of for its role in morbidity associated with sleep-disordered breathing, including central nervous system pathology. However, recent evidence suggests that the nervous system fights back in an...
Scott K Powers,Ashley J Smuder,Andreas N Kavazis et al.
Scott K Powers et al.
Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on cons...
Caroline Ronzaud,Olivier Staub
Caroline Ronzaud
Ubiquitylation is crucial for regulating numerous cellular functions. In the kidney, ubiquitylation regulates the epithelial Na(+) channel ENaC. The importance of this process is highlighted in Liddle's syndrome, where mutations interfere w...
Sympathetic neural regulation of blood pressure: influences of sex and aging [0.03%]
交感神经对血压的调节：性别和年龄的影响
E C J Hart,N Charkoudian
E C J Hart
Sex and age have important influences on sympathetic neural control of blood pressure in humans. Young women are relatively protected against risk of hypertension due to greater peripheral vasodilator influences compared with young men and ...
Gary Sieck
Gary Sieck
Virginia M Miller,Jane F Reckelhoff,Gary C Sieck
Virginia M Miller
Birmingham 2013 and beyond [0.03%]
伯明翰2013及以后
Denis Noble
Denis Noble