Gary Sieck
Gary Sieck
James A Levine
James A Levine
Germ cell transport across the seminiferous epithelium during spermatogenesis [0.03%]
生精过程中生殖细胞穿越生精上皮转移现象
Xiang Xiao,Dolores D Mruk,Chris K C Wong et al.
Xiang Xiao et al.
Transport of germ cells across the seminiferous epithelium is crucial to spermatogenesis. Its disruption causes infertility. Signaling molecules, such as focal adhesion kinase, c-Yes, c-Src, and intercellular adhesion molecules 1 and 2, are...
Qinghua Fang,Manfred Lindau
Qinghua Fang
The SNARE (Soluble NSF Attachment protein REceptor) complex, which in mammalian neurosecretory cells is composed of the proteins synaptobrevin 2 (also called VAMP2), syntaxin, and SNAP-25, plays a key role in vesicle fusion. In this review,...
Pirjo M Apaja,Gergely L Lukacs
Pirjo M Apaja
The plasma membrane (PM) and endocytic protein quality control (QC) in conjunction with the endosomal sorting machinery either repairs or targets conformationally damaged membrane proteins for lysosomal/vacuolar degradation. Here, we provid...
You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging [0.03%]
血管老化预防策略：动脉内皮细胞功能保护措施
Douglas R Seals,Rachelle E Kaplon,Rachel A Gioscia-Ryan et al.
Douglas R Seals et al.
Endothelial dysfunction develops with age and increases the risk of age-associated vascular disorders. Nitric oxide insufficiency, oxidative stress, and chronic low-grade inflammation, induced by upregulation of adverse cellular signaling p...
Adam C Straub,Angela C Zeigler,Brant E Isakson
Adam C Straub
A vast amount of investigation has centered on how the endothelium and smooth muscle communicate. From this evidence, myoendothelial junctions have emerged as critical anatomical structures to regulate heterocellular cross talk. Indeed, the...
Brenda Lilly
Brenda Lilly
Blood vessels are composed of two primary cell types, endothelial cells and smooth muscle cells, each providing a unique contribution to vessel function. Signaling between these two cell types is essential for maintaining tone in mature ves...
Robert Hooke: early respiratory physiologist, polymath, and mechanical genius [0.03%]
罗伯特·胡克：早期呼吸生理学家、博学者和机械天才
John B West
John B West
Robert Hooke (1635-1703) was a polymath who made important contributions to respiratory physiology and many other scientific areas. With Robert Boyle, he constructed the first air pump that allowed measurements on small animals at a reduced...