Nikki Forrester
Nikki Forrester
Kimberly L Dodge-Kafka,Moriah Gildart Turcotte,Sofia M Possidento et al.
Kimberly L Dodge-Kafka et al.
Canonical activation of G-protein coupled receptors (GPCRs) by hormone binding occurs at the plasma membrane, resulting in the diffusion of second messengers to intracellular effector sites throughout the cell. In contrast, recent evidence ...
Jing Chen,Yijia Xu,Peng Cao
Jing Chen
Accumulating evidence highlights the crucial role of the gut-brain axis in diseases. This bidirectional signaling connects the gastrointestinal tract (GI) and the brain via neural, immune, and endocrine pathways, orchestrating a range of ph...
What do we know of human fuel use during aerobic exercise and how do we know it? [0.03%]
有氧运动中人类能量底物利用的研究进展及展望
Jessie Axsom,Zolt Arany
Jessie Axsom
Aerobic exercise is arguably the most metabolically demanding challenge imposed on the human body. The metabolic adaptations to exercise are complex, involving most tissues, and differing substantially depending on the type, severity, and d...
Osama F Harraz,Ahmed M Hashad
Osama F Harraz
The brain relies on an intricate vascular network to deliver oxygen and nutrients through functional hyperemia, a process critical for matching blood flow to neuronal activity. This review explores the roles of ion channels in brain capilla...
Cigdem Sahin,Yu-Hua Tseng
Cigdem Sahin
Thermogenic adipose tissues, including brown and beige, exhibit remarkable cellular and metabolic adaptations to environmental and physiological cues, contributing to improved metabolic health. Among these adaptations, adipose progenitor ce...
Nikki Forrester
Nikki Forrester
Structures and Molecular Mechanisms of Insect Odorant and Gustatory Receptors [0.03%]
昆虫嗅觉和味觉受体的结构与分子机制
Xiangnan Zhang,Demin Ma,Jiangqin Wang et al.
Xiangnan Zhang et al.
Insects rely on chemoreceptors in sensory neurons to detect and discriminate various chemicals in constantly changing environments. Among the chemoreceptors, odorant receptors (ORs) and gustatory receptors (GRs) play essential roles in sens...
Growth hormone and IGF-1 actions in the brain and neuropsychiatric diseases [0.03%]
生长激素和IGF-1在大脑及神经精神疾病中的作用
Manuel H Aguiar-Oliveira,Margaret C S Boguszewski,Diego Luiz Rovaris et al.
Manuel H Aguiar-Oliveira et al.
Growth hormone (GH) is secreted by the anterior pituitary gland under the control of hypothalamic neuroendocrine neurons that express somatostatin or growth hormone-releasing hormone (GHRH). Ghrelin, originating primarily in the stomach, is...
Daniel Gagnon,Zachary J Schlader,Ollie Jay
Daniel Gagnon
A direct consequence of climate change is the intensification of hot weather and extreme heat events that are epidemiologically associated with a greater risk of heat-related illnesses and other adverse health outcomes, often resulting in s...