MFSD2A in focus: the molecular mechanism of omega-3 fatty acid transport [0.03%]
MFSD2A受关注的原因：Omega-3脂肪酸转运的分子机制
Farrah Blades,Aysenur Torun Yazici,Rosemary Jane Cater et al.
Farrah Blades et al.
Omega-3 fatty acids, such as docosahexaenoic acid (DHA), are essential nutrients required to support growth, maintenance, and function of the central nervous system (CNS). While the brain has a high demand for DHA, it cannot synthesize it d...
Nikki Forrester
Nikki Forrester
Lewis H Ziska
Lewis H Ziska
There is a fundamental need to consider plant physiology in relation to human health as it encompasses a number of often overlooked issues, from plant based medicines, to nutrition. The goal here is to provide a historical narrative of plan...
Harnessing Computational Strategies to Overcome Challenges in mRNA Vaccines [0.03%]
利用计算策略来克服mRNA疫苗中的挑战
Siyu Zhao,Jingjing Chen,Tian Dai et al.
Siyu Zhao et al.
In recent years, the introduction of mRNA vaccines for SARS-CoV2 and RSV has highlighted the success of the mRNA technology platform. Designing mRNA sequences involves multiple components and requires balancing several parameters, including...
Yuuta Imoto,Shigeki Watanabe
Yuuta Imoto
Endocytosis in non-neuronal cells requires gradual recruitment of proteins to endocytic sites for inducing membrane curvature and forming contractile scaffolds around the neck of endocytic pits. This recruitment process is thought to be rat...
Undernutrition-Associated Diabetes Mellitus: Pathophysiology of a Global Problem [0.03%]
与营养不良有关的糖尿病：全球性问题的病理生理学分析
Pradnyashree Wadivkar,Nihal Thomas,Felix Jebasingh et al.
Pradnyashree Wadivkar et al.
Early-life undernutrition is known to be a potentially important risk factor for the development of diabetes mellitus in adult life. Additionally, some literature suggests that undernutrition during later life or adulthood may lead to metab...
Yi-Hsuan Chiang,Stephan Emmrich,Nicola Vannini
Yi-Hsuan Chiang
Aging is a multifaceted process associated with a functional decline in cellular function over time, affecting all lifeforms. During the aging process, metabolism, a fundamental hallmark of life (1), is profoundly altered. In the context of...
Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome [0.03%]
肌痛性脑脊髓炎/慢性疲劳综合征中的线粒体功能障碍
Abu Mohammad Syed,Alexander K Karius,Jin Ma et al.
Abu Mohammad Syed et al.
ME/CFS is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms is prolonged fatigue following exertion, a feature also observed in long COVID, suggesting an underlying...
Synthetic forms most beautiful: engineering insights into self-organization [0.03%]
仿生结构最美丽：论自组织的工程学观点
Zhejing Xu,Chih-Chia Chang,Scott Coyle
Zhejing Xu
Reflecting on the diversity of the natural world, Darwin famously observed that "from so simple a beginning endless forms most beautiful and most wonderful have been, and are being evolved". However, the examples that we are able to observe...
Mark A Knepper
Mark A Knepper
Over the past several decades, physiological research has undergone a progressive shift toward greater-and-greater reductionism, culminating in the rise of 'molecular physiology.' The introduction of Omic techniques, chiefly protein mass sp...