Gary C Sieck
Gary C Sieck
Adiponectin Synthesis, Secretion and Extravasation from Circulation to Interstitial Space [0.03%]
脂蛋白脂肪酶的合成、分泌及从血液循环向组织间隙的转移
Simone C da Silva Rosa,Meilian Liu,Gary Sweeney
Simone C da Silva Rosa
Adiponectin, an adipokine that circulates as multiple multimeric complexes at high levels in serum, has antidiabetic, anti-inflammatory, antiatherogenic, and cardioprotective properties. Understanding the mechanisms regulating adiponectin's...
The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tête-à-Tête [0.03%]
衰老的肺部压力:内质网与细胞衰老面对面
M L Koloko Ngassie,C A Brandsma,R Gosens et al.
M L Koloko Ngassie et al.
Beyond the structural changes, features including the dysregulation of endoplasmic reticulum (ER) stress response and increased senescence characterize the lung aging. ER stress response and senescence have been reported to be induced by fa...
Intratumoral Hypoxia and Mechanisms of Immune Evasion Mediated by Hypoxia-Inducible Factors [0.03%]
肿瘤内的缺氧及由缺氧诱导因子介导的免疫逃逸机制
Gregg L Semenza
Gregg L Semenza
Activation of the innate and adaptive immune systems represents a promising strategy for defeating cancer. However, during tumor progression, cancer cells battle to shift the balance from immune activation to immunosuppression. Critical sit...
Physiological Societies Across the Globe Unite in an Effort to Handle the COVID-19 Pandemic [0.03%]
全球生理学学会团结一致应对新冠疫情
Susan M Barman,László Csernoch,Jayasree Sengupta
Susan M Barman
Vascular Endothelial Protein Tyrosine Phosphatase Regulates Endothelial Function [0.03%]
内皮细胞蛋白酪氨酸磷酸酶调节内皮功能
Dietmar Vestweber
Dietmar Vestweber
Vascular endothelial protein tyrosine phosphatase (VE-PTP) is a receptor-type PTP (RPTP), predominantly expressed in vascular endothelial cells. It regulates embryonic and tumor angiogenesis and controls vascular permeability and homeostasi...
Elisabeth Rohbeck,Juergen Eckel,Tania Romacho
Elisabeth Rohbeck
There is an urgent need for developing effective drugs to combat the obesity and Type 2 diabetes mellitus epidemics. The endocannabinoid system plays a major role in energy homeostasis. It comprises the cannabinoid receptors 1 and 2 (CB1 an...
Andrew S Neish
Andrew S Neish
It is now well understood that the eukaryotic host has evolved multiple mechanisms to monitor and respond to the diverse and biochemically active microbiota that thrives in a symbiotic fashion in the gut and other tissues. Generally, these ...
Gary C Sieck
Gary C Sieck
Roger M Enoka,Dario Farina
Roger M Enoka
Voluntary actions are controlled by the synaptic inputs that are shared by pools of spinal motor neurons. The slow common oscillations in the discharge times of motor units due to these synaptic inputs are strongly correlated with the fluct...