Sympathetic Innervation of White Adipose Tissue: to Beige or Not to Beige? [0.03%]
白色脂肪组织的交感神经支配：褐色或非褐色？
Heike Münzberg,Elizabeth Floyd,Ji Suk Chang
Heike Münzberg
Obesity research progresses in understanding neuronal circuits and adipocyte biology to regulate metabolism. However, the interface of neuro-adipocyte interaction is less studied. We summarize the current knowledge of adipose tissue innerva...
Caloric Restriction and Cardiovascular Health: the Good, the Bad, and the Renin-Angiotensin System [0.03%]
卡里克限制与心血管健康：肾素-血管紧张素系统的作用机制研究
Aline M A de Souza,Carolyn M Ecelbarger,Kathryn Sandberg
Aline M A de Souza
Much excitement exists over the cardioprotective and life-extending effects of caloric restriction (CR). This review integrates population studies with experimental animal research to address the positive and negative impact of mild and sev...
Gary C Sieck
Gary C Sieck
James C Poland,C Robb Flynn
James C Poland
Bile acids (BAs) are a family of hydroxylated steroids secreted by the liver that aid in the breakdown and absorption of dietary fats. BAs also function as nutrient and inflammatory signaling molecules, acting through cognate receptors, to ...
Aleksey Matveyenko,Gary Sieck,Amira Klip
Aleksey Matveyenko
Prefrontal Cortex Metabolome Is Modified by Opioids, Anesthesia, and Sleep [0.03%]
阿片类药物、麻醉和睡眠可改变前额叶皮质代谢组
Ralph Lydic,Helen A Baghdoyan
Ralph Lydic
Obtundation of wakefulness caused by opioids and loss of wakefulness caused by anesthetics and sleep significantly alter concentrations of molecules comprising the prefrontal cortex (PFC) metabolome. Quantifying state-selective changes in t...
Gary C Sieck
Gary C Sieck
Surviving in a Frozen Forest: the Physiology of Eastern Spruce Budworm Overwintering [0.03%]
东北松毛虫越冬的生理机制：严寒中的生存策略
Katie E Marshall,Amanda D Roe
Katie E Marshall
The eastern spruce budworm, Choristoneura fumiferana, is one of North America's most destructive forest insects. It survives the harsh winters by deploying both a sophisticated diapause program and a complex suite of cryoprotective molecule...
Robert Kavet,Joseph Brain
Robert Kavet
Species throughout the animal kingdom use the Earth's magnetic field (MF) to navigate using either or both of two mechanisms. The first relies on magnetite crystals in tissue where their magnetic moments align with the MF to transduce a sig...
Juan M Saavedra
Juan M Saavedra
Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune resp...