Compartmentalized nutrient and hormone sensing in β-cells: the role of cilia [0.03%]
β细胞中的营养物质和激素的区室化感应:纤毛的作用
Jing W Hughes,Matthew J Merrins
Jing W Hughes
Pancreatic β-cells couple nutrient and hormone sensing to insulin release. Prevailing models depict the β-cell as a homogeneous metabolic unit, overlooking specialized subcellular compartments like the primary cilium. Primary cilia are se...
David Tawiah
David Tawiah
Bong Ihn Koh,Ralf Adams
Bong Ihn Koh
Recent studies have uncovered that the calvarial bone marrow (BM), located within the skull, functions as a specialized hematopoietic niche distinct from BM in long bones. This compartment supports a unique repertoire of immune cells, parti...
Abida Islam Pranty,Sara Cuevas Ocaña,Jennifer A Dickens
Abida Islam Pranty
Pulmonary surfactant is a lipoproteinaceous material secreted exclusively by alveolar type 2 cells into the alveolar space. It is primarily responsible for reducing the work of breathing by reducing surface tension at the air-liquid interfa...
Dong Jiang,Li Yu
Dong Jiang
Migrasomes are specialized organelle that form during cell migration and play a critical role in intercellular communication and disease progression. First discovered in 2012 and reported in 2015, these organelles are characterized by their...
Tension to Translation: External to Internal Processes in Muscle Hypertrophy [0.03%]
从张力到翻译:肌肉肥大过程中外部刺激与内部反应的关系
Dominique Greyvenstein,James P Newbold,Stuart M Phillips
Dominique Greyvenstein
Skeletal muscle is a highly adaptable tissue that plays a central role in overall health. The dynamic balance between muscle protein synthesis and breakdown governs skeletal muscle mass maintenance. Increased loading and hyperaminoacidemia ...
Favian Andres Morales
Favian Andres Morales
Mohammad Irshad Reza
Mohammad Irshad Reza
Jenna B Goulart
Jenna B Goulart
Ryan Nestor Montalvo
Ryan Nestor Montalvo