BEAST X for Bayesian phylogenetic, phylogeographic and phylodynamic inference [0.03%]
贝叶斯生物信息学综合分析软件BEAST X
Guy Baele,Xiang Ji,Gabriel W Hassler et al.
Guy Baele et al.
Here we present the open-source and cross-platform BEAST X software that combines molecular phylogenetic reconstruction with complex trait evolution, divergence-time dating and coalescent demographics in an efficient statistical inference e...
Interpretable representation learning for 3D multi-piece intracellular structures using point clouds [0.03%]
基于点云的可解释表示学习用于理解细胞内的三维多组件结构
Ritvik Vasan,Alexandra J Ferrante,Antoine Borensztejn et al.
Ritvik Vasan et al.
A key challenge in understanding subcellular organization is quantifying interpretable measurements of intracellular structures with complex multi-piece morphologies in an objective, robust and generalizable manner. Here we introduce a morp...
Siewert Hugelier
Siewert Hugelier
A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data [0.03%]
一种变换器模型用于数据非依赖性采集质谱数据的从头测序
Justin Sanders,Bo Wen,Paul A Rudnick et al.
Justin Sanders et al.
A core computational challenge in the analysis of mass spectrometry data is the de novo sequencing problem, in which the generating amino acid sequence is inferred directly from an observed fragmentation spectrum without the use of a sequen...
John S H Danial
John S H Danial
Super-resolution microscopy (SRM) has revolutionized biological imaging, enabling the visualization of biological structures at molecular resolution. However, the diversity of SRM techniques, each operating through different mechanisms, com...
Justin T Seffernick,Marcus Fischer
Justin T Seffernick
Understanding protein hydration at the atomic level is a hallmark challenge in deciphering ligand binding and guiding ligand discovery. The fact that 95% of deposited crystal structures are cryogenic currently limits the utility of crystall...
CryoDRGN-AI: neural ab initio reconstruction of challenging cryo-EM and cryo-ET datasets [0.03%]
CryoDRGN-AI：具有挑战性的冷冻电镜和低温断层扫描数据集的神经从头重建技术
Axel Levy,Rishwanth Raghu,J Ryan Feathers et al.
Axel Levy et al.
Proteins and other biomolecules form dynamic macromolecular machines that are tightly orchestrated to move, bind and perform chemistry. Cryo-electron microscopy and cryo-electron tomography can access the intrinsic heterogeneity of these co...
Kez Cleal,Alexander Kearsey,Duncan M Baird
Kez Cleal
A sweet summer of science [0.03%]
甜蜜的科学之夏
Vivien Marx
Vivien Marx
How to spy on condensates [0.03%]
如何探测凝聚体
Vivien Marx
Vivien Marx