NirFAP680: a highly bright and stable large Stokes shift near-infrared fluorogen-activating protein [0.03%]
NirFAP680：一种高度亮且稳定的大型斯托克斯偏移近红外荧光活化蛋白
Zhengda Chen,Li Jiang,Xiaoyu Liu et al.
Zhengda Chen et al.
Near-infrared (NIR) genetically encoded fluorescent tags are superior for new imaging capabilities ranging from multiplexed imaging to deep-tissue imaging. Here, we describe the development of NirFAP680; NirFAP680 is an NIR fluorogen-activa...
Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problem [0.03%]
外泌体分析中的多因素认证：解决异质性问题的方法和思路
Quan Zhou,Richard J Lobb,Alain Wuethrich et al.
Quan Zhou et al.
Extracellular vesicles (EVs) are essential for intercellular communication and various physiological processes; however, they are difficult to reliably identify and characterize owing to their inherent heterogeneity. To address this challen...
Vivien Marx
Vivien Marx
Jun Wang,Dinghai Zheng,Vikram Agarwal
Jun Wang
Philip Fradkin,Ruian Ian Shi,Taykhoom Dalal et al.
Philip Fradkin et al.
In the face of rapidly accumulating genomic data, our ability to predict key mature RNA properties that underlie transcript function and regulation remains limited. Pretrained genomic foundation models offer an avenue to adapt learned RNA r...
Designer indicators for two-photon recording of subthreshold voltage dynamics [0.03%]
用于两光子记录亚阈值电压动态的设计指标
Michelle A Land,Mario Galdamez,Vincent Villette et al.
Michelle A Land et al.
Subthreshold voltage dynamics are essential for neuronal information integration, yet they remain technically challenging to measure in vivo. While genetically encoded voltage indicators are emerging as powerful tools for voltage recording,...
Katie L Holland,Sarah E Plutkis,Brian P English et al.
Katie L Holland et al.
Spontaneously blinking fluorophores toggle between nonfluorescent and fluorescent forms without caging groups or redox buffers, enabling super-resolution imaging. The intrinsic blinking of such dyes is governed by molecular structure and mo...
Aparna Anantharaman
Aparna Anantharaman
Fariha Rahman
Fariha Rahman
Host-microbiome maps [0.03%]
宿主-微生物组图谱
Madhura Mukhopadhyay
Madhura Mukhopadhyay