Julia Peukes
Julia Peukes
Vivien Marx
Vivien Marx
A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms [0.03%]
一种用于从分子到活体器官的多模态自适应光学显微镜
Tian-Ming Fu,Gaoxiang Liu,Daniel E Milkie et al.
Tian-Ming Fu et al.
Understanding biological systems requires observing features and processes across vast spatial and temporal scales, spanning nanometers to centimeters and milliseconds to days, often using multiple imaging modalities within complex native m...
Author Correction: Biophysical prediction of protein-peptide interactions and signaling networks using machine learning [0.03%]
作者更正:使用机器学习预测生物物理蛋白质-肽相互作用和信号网络
Joseph M Cunningham,Grigoriy Koytiger,Peter K Sorger et al.
Joseph M Cunningham et al.
Published Erratum
Nature methods. 2026 May 21. DOI:10.1038/s41592-026-03117-7 2026
StringTie3 improves total RNA-seq assembly by resolving nascent and mature transcripts [0.03%]
StringTie3通过解析新生和成熟的转录物改进总RNA测序组装
Ida Shinder,Geo Pertea,Richard Hu et al.
Ida Shinder et al.
Accurate assembly of rRNA-depleted (total) RNA sequencing (RNA-seq) remains challenging because existing methods often conflate incomplete, nascent RNA with fully processed mature isoforms, leading to misassemblies and quantification errors...
Stephanie A Wankowicz,Massimiliano Bonomi
Stephanie A Wankowicz
Proteins and other macromolecules exist as dynamic ensembles of interconverting conformations essential for catalysis, allosteric regulation and molecular recognition. While AI tools like AlphaFold have revolutionized static structure predi...
Recommendations and considerations for hydroxyl radical protein footprinting-mass spectrometry [0.03%]
羟基自由基蛋白质足迹分析-质谱法的建议和考虑事项
Aaron T Wecksler,Lingfei Wang,Lisa J Bernstein et al.
Aaron T Wecksler et al.
Protein oxidative footprinting, using hydroxyl radical labeling detected by bottom-up proteomics, has progressed from an emerging method to a widely used approach in structural biology. Hydroxyl radicals generated from hydrogen peroxide (vi...
Unraveling lncRNA diversity at a single cell resolution and in a spatial context across different cancer types [0.03%]
解析不同类型癌症中单细胞分辨率下的长链非编码 RNA 多样性及其空间背景
P Prakrithi,Tuan Vo,Zherui Xiong et al.
P Prakrithi et al.
Long noncoding RNAs (lncRNAs) participate in gene regulation underlying development and disease. Overcoming inherent limitations of bulk sequencing lncRNA analysis, we leveraged single-cell and spatial transcriptomics (ST) data to analyze 2...
Lin Tang
Lin Tang
Whole mouse mapping [0.03%]
完整的鼠标映射
Madhura Mukhopadhyay
Madhura Mukhopadhyay