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期刊名:Nature methods

缩写:NAT METHODS

ISSN:1548-7091

e-ISSN:1548-7105

IF/分区:28.3/Q1

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共收录本刊相关文章索引5778
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Tian-Ming Fu,Gaoxiang Liu,Daniel E Milkie et al. Tian-Ming Fu et al.
Understanding biological systems requires observing features and processes across vast spatial and temporal scales, spanning nanometers to centimeters and milliseconds to days, often using multiple imaging modalities within complex native m...
Ida Shinder,Geo Pertea,Richard Hu et al. Ida Shinder et al.
Accurate assembly of rRNA-depleted (total) RNA sequencing (RNA-seq) remains challenging because existing methods often conflate incomplete, nascent RNA with fully processed mature isoforms, leading to misassemblies and quantification errors...
Stephanie A Wankowicz,Massimiliano Bonomi Stephanie A Wankowicz
Proteins and other macromolecules exist as dynamic ensembles of interconverting conformations essential for catalysis, allosteric regulation and molecular recognition. While AI tools like AlphaFold have revolutionized static structure predi...
Aaron T Wecksler,Lingfei Wang,Lisa J Bernstein et al. Aaron T Wecksler et al.
Protein oxidative footprinting, using hydroxyl radical labeling detected by bottom-up proteomics, has progressed from an emerging method to a widely used approach in structural biology. Hydroxyl radicals generated from hydrogen peroxide (vi...
P Prakrithi,Tuan Vo,Zherui Xiong et al. P Prakrithi et al.
Long noncoding RNAs (lncRNAs) participate in gene regulation underlying development and disease. Overcoming inherent limitations of bulk sequencing lncRNA analysis, we leveraged single-cell and spatial transcriptomics (ST) data to analyze 2...