High-throughput profiling of chemical-induced gene expression across 93,644 perturbations [0.03%]
高通量化学诱导基因表达谱分析研究在93644种干扰下进行
Lei Xiang,Yumei Wang,Wei Shao et al.
Lei Xiang et al.
In this Resource, we present an extensive dataset of chemical-induced gene signatures (CIGS), encompassing expression patterns of 3,407 genes regulating key biological processes in 2 human cell lines exposed to 13,221 compounds across 93,66...
Co-profiling of in situ RNA-protein interactions and transcriptome in single cells and tissues [0.03%]
单细胞和组织中的RNA-蛋白质相互作用的原位共分析及转录组分析
Qi-Xuan Cheng,Gang Xie,Xiangyu Zhang et al.
Qi-Xuan Cheng et al.
RNA-binding proteins (RBPs) are essential regulators of RNA fate and function. A long-standing challenge in studying RBP regulation has been mapping RNA interactomes within the dynamic transcriptomic landscape, especially in single-cell con...
Author Correction: A universal language for finding mass spectrometry data patterns [0.03%]
作者更正：寻找质谱数据模式的通用语言
Tito Damiani,Alan K Jarmusch,Allegra T Aron et al.
Tito Damiani et al.
Published Erratum
Nature methods. 2025 Aug 8. DOI:10.1038/s41592-025-02785-1 2025
Dominik Vonficht,Lea Jopp-Saile,Schayan Yousefian et al.
Dominik Vonficht et al.
Cellular interactions are of fundamental importance, orchestrating organismal development, tissue homeostasis and immunity. Recently, powerful methods that use single-cell genomic technologies to dissect physically interacting cells have be...
Srinivas Niranj Chandrasekaran,Eric Alix,John Arevalo et al.
Srinivas Niranj Chandrasekaran et al.
Cell Painting images offer valuable insights into a cell's state and enable many biological applications, but publicly available arrayed datasets only include hundreds of genes perturbed. The JUMP Cell Painting Consortium perturbed roughly ...
Nina Vogt
Nina Vogt
Lin Tang
Lin Tang