Aparna Anantharaman
Aparna Anantharaman
CATCHing off-target drugs [0.03%]
抓住脱靶药物
Fariha Rahman
Fariha Rahman
Lin Tang
Lin Tang
Nina Vogt
Nina Vogt
Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny [0.03%]
纠正SARS-CoV-2系统发生树中的大流行范围内的系统误差
Martin Hunt,Angie S Hinrichs,Daniel Anderson et al.
Martin Hunt et al.
The majority of SARS-CoV-2 genomes obtained during the pandemic were derived by amplifying overlapping windows of the genome ('tiled amplicons'), reconstructing their sequences and fitting them together. This leads to systematic errors in g...
Rate variation and recurrent sequence errors in pandemic-scale phylogenetics [0.03%]
大流行规模下的疫情率变化与重复序列错误
Nicola De Maio,Myrthe Willemsen,Samuel Martin et al.
Nicola De Maio et al.
Phylogenetic analyses of genome sequences from infectious pathogens reveal essential information regarding their evolution and transmission, as seen during the coronavirus disease 2019 pandemic. Recently developed pandemic-scale phylogeneti...
Deep-coverage single-cell metabolomics enabled by ion mobility-resolved mass cytometry [0.03%]
基于离子淌度分辨式的质谱细胞分析实现单细胞代谢组高覆盖检测
Mingdu Luo,Tianzhang Kou,Yandong Yin et al.
Mingdu Luo et al.
Current single-cell metabolomics approaches are limited by insufficient sensitivity, robustness and metabolite coverage. We present an ion mobility-resolved mass cytometry technology that integrates high-throughput single-cell injection wit...