Junwei Zhang,Kecheng Zhang,Kui Wang et al.
Junwei Zhang et al.
Organic fluorophores are the keystone of advanced biological imaging. The vast chemical space of fluorophores has been extensively explored in search of molecules with ideal properties. However, within the current molecular constraints, the...
Frederik Brøndsted,Lei G Wang
Frederik Brøndsted
Tsai-Wen Chen,Xian-Bin Huang,Sarah E Plutkis et al.
Tsai-Wen Chen et al.
Voltage imaging is a promising technique for high-speed recording of neuronal population activity. However, tissue scattering severely limits its application in dense neuronal populations. Here we adopt the principle of localization microsc...
Ultrafast and accurate sequence alignment and clustering of viral genomes [0.03%]
超快且准确的病毒基因组序列比对和聚类
Andrzej Zielezinski,Adam Gudyś,Jakub Barylski et al.
Andrzej Zielezinski et al.
Viromics produces millions of viral genomes and fragments annually, overwhelming traditional sequence comparison methods. Here we introduce Vclust, an approach that determines average nucleotide identity by Lempel-Ziv parsing and clusters v...
Digitalized organoids: integrated pipeline for high-speed 3D analysis of organoid structures using multilevel segmentation and cellular topology [0.03%]
数字化类器官:基于多层次分割和细胞拓扑的高通量三维分析类器官结构的集成管线
Hui Ting Ong,Esra Karatas,Titouan Poquillon et al.
Hui Ting Ong et al.
Organoids replicate tissue architecture and function and offer a unique opportunity to explore the impact of external perturbations in vitro. However, conducting large-scale screening procedures to investigate the effects of various stresse...
Xinyi Zhang,Yitong Tseo,Yunhao Bai et al.
Xinyi Zhang et al.
The subcellular localization of a protein is important for its function, and its mislocalization is linked to numerous diseases. Existing datasets capture limited pairs of proteins and cell lines, and existing protein localization predictio...
Madhura Mukhopadhyay
Madhura Mukhopadhyay
Nina Vogt
Nina Vogt
Lei Tang
Lei Tang