Paul W Denton,J Victor Garcia
Paul W Denton
There are few models in which HIV pathogenesis, particularly gut-associated lymphoid tissue CD4(+) T-cell depletion, can be studied and in which potential clinical interventions against HIV disease can be evaluated. HIV cannot be studied in...
Andrea Lisco,Christophe Vanpouille,Leonid Margolis
Andrea Lisco
The human body constitutes a balanced ecosystem of its own cells together with various microbes ("host-microbe ecosystem"). The transmission of HIV-1 and the progression of HIV disease in such an ecosystem are accompanied by de novo infecti...
Head-to-head comparison of two first-line regimens and an NRTI-sparing regimen for initial therapy of HIV-1 infection: what should we start? [0.03%]
初始治疗HIV-1感染的两种一线方案及不含核苷类似物反转 transcriptase 抑制剂(NRTI)方案的比较:我们应该如何开始?
David L Pitrak
David L Pitrak
Comparative Study
Current HIV/AIDS reports. 2009 Feb;6(1):1-2. DOI:10.1007/s11904-009-0001-4 2009
Variations in sexual risks in drug users: emerging themes in a behavioral context [0.03%]
药物使用者中的性行为风险变化:行为背景下的新主题
David D Celentano,Amanda D Latimore,Shruti H Mehta
David D Celentano
Drug users are an especially complex population among those studied in HIV risk behavior research. Although injection drug use accounts for over one third of the cumulative HIV transmission in the United States, the scope of the direct and ...
Jessica Foley,Mark Ettenhofer,Matthew Wright et al.
Jessica Foley et al.
Neurocognitive compromise, a common sequela of HIV infection, ranges in severity from minor motor and information-processing speed decrements to severely incapacitating symptoms that affect functional independence. However, with the emergen...
The information-motivation-behavioral skills model of antiretroviral adherence and its applications [0.03%]
基于信息-动机-行为能力模式的艾滋病患者抗病毒治疗服药研究及其应用展望
Jeffrey D Fisher,K Rivet Amico,William A Fisher et al.
Jeffrey D Fisher et al.
Suboptimal adherence to highly active antiretroviral therapy (HAART) may have serious consequences for HIV patients, and for public health overall. The Information-Motivation-Behavioral Skills (IMB) model of HAART adherence can be used to u...
Adherence to biomedical HIV prevention methods: considerations drawn from HIV treatment adherence research [0.03%]
从艾滋病治疗依从性研究中获得的关于坚持使用生物医学艾滋病预防方法的考虑因素
Michael J Stirratt,Christopher M Gordon
Michael J Stirratt
Biomedical approaches to HIV prevention (eg, microbicides, antiretroviral preexposure prophylaxis) are undergoing clinical trials to test their efficacy. One key consideration emerging from completed trials is the critical role of adherence...
Attrition and related trends in scientific rigor: a score card for ART adherence intervention research and recommendations for future directions [0.03%]
科研严谨性的流失及相关的趋势:评估行为干预研究并为未来研究提供建议评分表
K Rivet Amico,Jennifer J Harman,Megan A OGrady
K Rivet Amico
Scientific rigor in intervention trials is frequently used in systems that identify effective interventions for dissemination. In these systems, and in work that synthesizes bodies of research, percent attrition is often considered a fatal ...
Judith G Rabkin
Judith G Rabkin
Since the earliest days of the AIDS epidemic, clinicians have been concerned about the prevalence of depression among their patients. Epidemiologists, psychiatrists, psychologists, sociologists, and a broad array of other specialists have s...
Kavita P Bhavan,Vinay N Kampalath,Edgar Turner Overton
Kavita P Bhavan
Since the advent of highly active antiretroviral therapy, life expectancies for persons with HIV infection are similar to those for uninfected people. A growing proportion of HIV-infected individuals are now over the age of 50. We are also ...