The burden of diabetes and hyperlipidemia in treated HIV infection and approaches for cardiometabolic care [0.03%]
治疗HIV感染的糖尿病和高脂血症负担及心血管代谢照护方法
Katherine Samaras
Katherine Samaras
Treatment of HIV infection with highly active antiretroviral therapy (HAART) confers survival and quality of life benefits. However, these significant benefits are at the cost of metabolic complications with associated increased risk of typ...
Human papillomavirus vaccines: where do they fit in HIV-infected individuals? [0.03%]
人乳头瘤病毒疫苗：在HIV感染者中如何使用？
Cynthia Firnhaber,Timothy Wilkin
Cynthia Firnhaber
Human papillomavirus (HPV) is the etiological agent for cervical cancer and a large majority of anal cancers worldwide. In 2006 two preventive vaccines against the HPV were approved by the US Food and Drug Administration and have since been...
When to start ART in the setting of acute AIDS-related opportunistic infections: the time is now! [0.03%]
活动性艾滋病相关机会感染患者何时开始抗病毒治疗：时机已到！
Philip M Grant,Andrew R Zolopa
Philip M Grant
Despite the substantial benefits of combination antiretroviral therapy (ART), a significant proportion of HIV-infected individuals still present with advanced disease and active AIDS-related opportunistic infections (OIs). The weight of evi...
Jose M Miro,Federico Cofan,Joan C Trullas et al.
Jose M Miro et al.
Antiretroviral therapy has been immensely successful in reducing the incidence of opportunistic infections and death after HIV infection. This has resulted in heightened interest in noninfectious comorbidities including kidney disease. Alth...
Markella V Zanni,Steven K Grinspoon
Markella V Zanni
HIV + patients face a heightened risk of cardiovascular disease (CVD), which cannot be fully explained by traditional risk factors or antiretroviral therapy (ART)-related cardiotoxicity. Increasing evidence suggests a significant contributi...
Hepatitis C and HIV co-infection: new drugs in practice and in the pipeline [0.03%]
丙型肝炎和艾滋病合并感染：已投入应用及正在研发的新药
Carrie L Jennings,Kenneth E Sherman
Carrie L Jennings
HCV/HIV coinfection continues to represent a serious health issue with risk of liver disease progression and development of hepatocellular carcinoma. Pegylated interferon with ribavirin is approved for treatment but results are suboptimal a...
Alan R Lifson,Harry A Lando
Alan R Lifson
Health hazards due to smoking may undermine benefits of HIV treatment on morbidity and mortality. Over 40% of persons with HIV are current smokers. Health risks of smoking include increases in some HIV-associated infections, cardiovascular ...
Treatment of latent tuberculosis infection in HIV: shorter or longer? [0.03%]
HIV感染者LTBI的短程与长程治疗效果如何？
Anna K Person,Timothy R Sterling
Anna K Person
Nine months of daily isoniazid is efficacious in treating latent M. tuberculosis infection, but completion rates are low, limiting treatment effectiveness. In 2011, three important studies were published involving novel regimens for the tre...
William G Powderly
William G Powderly
Patients with HIV can develop several complications that involve bone including low bone mineral density and osteoporosis, osteonecrosis, and rarely osteomalacia. Low bone mineral density leading to osteoporosis is the most common bone path...
Peter W Hunt
Peter W Hunt
Persistent immune activation and inflammation despite sustained antiretroviral therapy (ART)-mediated viral suppression has emerged as a major challenge of the modern HIV treatment era. While immune activation, inflammatory, and coagulation...