HIV Compartmentalization in the CNS and Its Impact in Treatment Outcomes and Cure Strategies [0.03%]
HIV在中枢神经系统中的区室化及其对治疗效果和治愈策略的影响
Phillip Chan,Serena Spudich
Phillip Chan
Purpose of review: This review focuses on the cerebrospinal fluid (CSF) findings in connection to the central nervous system (CNS) reservoir in treatment-naïve and virally suppressed PLWH, followed by the findings in CSF...
Radhika Sundararajan,Matthew Ponticiello,Denis Nansera et al.
Radhika Sundararajan et al.
Purpose of review: HIV testing is the critical first step to direct people living with HIV (PLWH) to treatment. However, progress is still being made towards the UNAIDS benchmark of 95% of PLWH knowing their status by 203...
Viral and Host Biomarkers of HIV Remission Post Treatment Interruption [0.03%]
中断治疗后的HIV缓解的病毒和宿主生物标志物
Leila B Giron,Mohamed Abdel-Mohsen
Leila B Giron
Purpose of review: HIV rebound/remission after antiretroviral therapy (ART) interruption is likely influenced by (a) the size of the inducible replication-competent HIV reservoir and (b) factors in the host environment th...
HIV-1 Reservoir Persistence and Decay: Implications for Cure Strategies [0.03%]
人类免疫缺陷病毒I型储存源的持续与消退：对根治策略的意义
Edward F Kreider,Katharine J Bar
Edward F Kreider
Purpose of review: Despite suppressive antiretroviral therapy (ART), a viral reservoir persists in individuals living with HIV that can reignite systemic replication should treatment be interrupted. Understanding how HIV-...
COVID-19 Clinical Presentation Among HIV-Infected Persons in China: A Systematic Review [0.03%]
中国HIV感染者新冠病毒肺炎临床特点的系统综述
Dayong Huang,Jiawulan Zunong,Menglong Li et al.
Dayong Huang et al.
Purpose of review: The impact of HIV infection on the natural history of COVID-19 is unknown, given the recency of the human spread of SARS-CoV-2 (CoV). We reviewed published case series/reports of CoV-HIV coinfections to...
Monique J Brown,Oluwafemi Adeagbo
Monique J Brown
Purpose of review: The prevalence of trauma is higher among people living with HIV compared to the general population and people living without HIV. Trauma may be a major barrier in attaining HIV treatment outcomes, such ...
Caroline E Diggins,Samuel C Russo,Janet Lo
Caroline E Diggins
Purpose of review: This review reports on published studies describing metabolic changes associated with antiretroviral therapy (ART) to treat HIV disease including a historical perspective of earlier ART agents, but with...
Intersecting Pandemics of HIV and SARS-CoV-2: Commentary on the Special Issue [0.03%]
关于特刊的评论：HIV和SARS-CoV-2互为交织的流行病学问题
Sten H Vermund
Sten H Vermund
Purpose of review: This editorial introduces this special Global Health Section on the interface of the HIV/AIDS and COVID-19 pandemics. Recent findings: ...
Risk-Based Screening Tools to Optimise HIV Testing Services: a Systematic Review [0.03%]
基于风险的筛查工具优化HIV检测服务：系统评价研究
J J Ong,K Coulthard,C Quinn et al.
J J Ong et al.
Purpose of review: Effective ways to diagnose the remaining people living with HIV who do not know their status are a global priority. We reviewed the use of risk-based tools, a set of criteria to identify individuals who...
HIV and SARS-CoV-2 Co-infection: Epidemiological, Clinical Features, and Future Implications for Clinical Care and Public Health for People Living with HIV (PLWH) and HIV Most-at-Risk Groups [0.03%]
HIV和SARS-CoV-2合并感染：流行病学、临床特征及对未来医疗服务和公共卫生活着的HIV感染者（PLWH）和HIV高危人群的影响
D K Nomah,J Reyes-Urueña,J M Llibre et al.
D K Nomah et al.
Purpose of review: The purpose of this review is to use the currently available clinical and epidemiological data, to identify key aspects to improve both the clinical management and public health response to SARS-CoV-2/H...