Defining the Global Research and Programmatic Agenda and Priority Actions for Voluntary Medical Male Circumcision for HIV Prevention [0.03%]
自愿男性包皮环切手术在艾滋病预防中的全球研究和项目重点及行动建议定义
Megan E Peck,Todd Lucas,Katherine S Ong et al.
Megan E Peck et al.
Purpose of review: Since 2007, voluntary medical male circumcision (VMMC) programs have been associated with substantially reduced HIV incidence across 15 prioritized countries in Eastern and Southern Africa. Drawing on t...
The Effects of Medical Male Circumcision on Female Partners' Sexual and Reproductive Health [0.03%]
男性医疗包皮环切对女性伴侣性与生殖健康的影响
Supriya D Mehta
Supriya D Mehta
Purpose of review: Voluntary medical male circumcision (VMMC) reduces the risk of HIV acquisition by 60% among heterosexual men, provides protection against certain sexually transmitted infections (STI), and leads to peni...
Yanxiao Gao,Yinghui Sun,Weiran Zheng et al.
Yanxiao Gao et al.
Purpose of review: Evidence from clinical trials identified the effectiveness of voluntary medical male circumcision (VMMC) as an additional strategy to reduce the risk of HIV transmission from women to men. However, conc...
Voluntary Medical Male Circumcision for HIV Prevention: a Global Overview [0.03%]
为预防艾滋病而进行的自愿医疗男割礼：全球综述
Chen Zhang,Sten H Vermund
Chen Zhang
Purpose of review: With the promise of HIV prevention, there has been a scale-up of voluntary medical male circumcision (VMMC) in high HIV incidence/low circumcision prevalence nations worldwide. Nonetheless, debates over...
Consolidated Overview of Notifiable Adverse Events in the U.S. President's Emergency Plan for AIDS Relief's Voluntary Medical Male Circumcision Program Through 2020 [0.03%]
美国艾滋病救济紧急计划的自愿医疗男性包皮环切项目中2020年之前的可报告不利事件综合概述
Todd Lucas,Caroline Cooney,Amber Prainito et al.
Todd Lucas et al.
Purpose of review: Through December 2020, the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) supported more than 25 million voluntary medical male circumcisions (VMMC) as part of the combined HIV prevention stra...
Amanda J Jones,Jyoti S Mathad,Kelly E Dooley et al.
Amanda J Jones et al.
Purpose of review: Pregnant people living with HIV (PLWH) are at especially high risk for progression from latent tuberculosis infection (LTBI) to active tuberculosis (TB) disease. Among pregnant PLWH, concurrent TB incre...
Jessica L Prodger,Ronald M Galiwango,Aaron A R Tobian et al.
Jessica L Prodger et al.
Purpose of review: Voluntary medical male circumcision (VMMC) is a surgical procedure that reduces HIV acquisition risk by almost two-thirds. However, global implementation is lagging, in part due to VMMC hesitancy. A bet...
Trends and Clinical Characteristics of HIV and Cerebrovascular Disease in Low- and Middle-Income Countries (LMICs) Between 1990 and 2021 [0.03%]
1990至2021年低收入和中等收入国家HIV及相关脑血管疾病的流行趋势及临床特征
George Ransley,Stanley Zimba,Yohane Gadama et al.
George Ransley et al.
Purpose of the review: To describe trends and clinical characteristics of HIV and cerebrovascular disease between 1990 and 2021 in LMICs and identify the gaps in our understanding. ...
Lessons for Understanding Central Nervous System HIV Reservoirs from the Last Gift Program [0.03%]
“过去礼物项目”对中枢神经系统HIV储存库的理解启示
Patricia K Riggs,Antoine Chaillon,Guochun Jiang et al.
Patricia K Riggs et al.
Purpose of review: Deep tissue HIV reservoirs, especially within the central nervous system (CNS), are understudied due to the challenges of sampling brain, spinal cord, and other tissues. Understanding the cellular chara...
Promise and Challenges of Checkpoint Inhibitor Therapy for Progressive Multifocal Leukoencephalopathy in HIV [0.03%]
HIV患者进行性多灶性白质脑病接受免疫检验点抑制剂治疗的前景与挑战
Sydney Corey,Bryan R Smith,Irene C M Cortese
Sydney Corey
Purpose of review: Progressive multifocal leukoencephalopathy (PML) is a severe opportunistic infection that remains an important cause of morbidity and mortality in people living with HIV (PLWH). Immune checkpoint molecu...