Associations between patient risk factors, disease severity, and inflammatory markers in community-acquired pneumonia [0.03%]
社区获得性肺炎患者危险因素、病情严重程度与炎症标志物之间的关联分析
Ruta Nutautiene,Irmantas Aleksa,Ieva Janulaityte et al.
Ruta Nutautiene et al.
Community-acquired pneumonia (CAP) remains a major cause of morbidity and mortality, particularly in older adults and patients with chronic co-morbidities. Cytokine patterns and simple hematological indices may improve risk stratification b...
Robert V House,Marc J Pallardy
Robert V House
The beneficial properties of glycomacropeptide in management of atopic dermatitis and extenuating skin aging [0.03%]
甘露聚肽在特应性皮炎和缓解皮肤衰老中的有益性质研究
Lida Majidinia,Ladan Majidinia,Ahmad Kalbasi-Ashtari
Lida Majidinia
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by impaired skin barrier function, persistent inflammation, and increased vulnerability to environmental irritants. Chronic inflammation in AD can also contribute ...
Evaluation of the immunotoxicity of atrazine and its chloro-metabolites: relevance for human cancer [0.03%]
阿特拉津及其氯代代谢产物免疫毒性的评估及与人类癌症的相关性
Charles Breckenridge,James W Simpkins,Ralph Cooper
Charles Breckenridge
This review was undertaken because it is known that high doses of atrazine activate the HPA axis, leading to increased corticosterone secretion, which could result in immunosuppression. The mammalian immunotoxicity of atrazine was evaluated...
Modification of the dextran sodium sulfate model to identify agents that induce or exacerbate inflammatory bowel disease [0.03%]
改良dextran硫酸钠模型以筛选诱导或加重肠道炎症的物质
Victor J Johnson,Michael I Luster,Michael Kashon et al.
Victor J Johnson et al.
Exposure to environmental agents has been linked to inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD) in humans. In these studies, we describe a modification of an experimental model used historica...
Association between CD200 molecule expression on B lymphocytes and levels of specific IgE against molecular components of storage mites, animals and molds in atopic dermatitis patients [0.03%]
特应性皮炎患者B淋巴细胞CD200分子表达与尘仓螨、动物和霉菌分子组分特异性IgE水平的相关性研究
Jarmila Čelakovská,Eva Čermáková,Petra Boudková et al.
Jarmila Čelakovská et al.
This study investigated the relationship between CD200 molecule expression on B- lymphocytes and the levels of specific IgE to molecular components of storage mites (Gly d 2, Lep d 2), dog (Can f 1, Can f 2), cat (Fel d 1), shrimp (Pen m 2)...
Soy allergy in patients with atopic dermatitis, sensitivity of ALEX2 Allergy Xplorer examination [0.03%]
ALEX2 Allergy Xplorer检测在特应性皮炎患者中的大豆过敏筛查价值分析
Jarmila Čelakovská,Eva Čermáková,Ctirad Andrýs et al.
Jarmila Čelakovská et al.
The aim of the current study was to evaluate the incidence of soy allergy in patients with atopic dermatitis (AD) and to evaluate the results of specific IgE against molecular components of soy. Altogether, 100 AD patients were examined. So...
Interaction between expression of CD23 on B-lymphocytes and level of specific IgE against molecular components of NPC2 family, lipocalins, uteroglobins, and molecular components of molds and yeast [0.03%]
CD23在B淋巴细胞上的表达与针对NPC2家族、脂质运载蛋白、uteroglobin和霉菌及酵母属分子成分的特异性IgE水平之间的关系
Jarmila Čelakovská,Petra Boudkova,Eva Cermakova et al.
Jarmila Čelakovská et al.
The aim of this study was to assess the relationship between the expression of the CD23 molecule on B-cells and the levels of specific IgE against allergens and molecular components of storage mites (Gly d 2, Lep d 2), dog (Can f 1, Can f 2...
Comparable immunogenicity of new modality biotherapeutics delivered subcutaneously or intravenously in non-human primates [0.03%]
新的生物制剂治疗模式在非人灵长类动物中皮下或静脉注射的免疫原性可比性
Victoria Koch,Martin Lechmann,Katharine Bray-French et al.
Victoria Koch et al.
Unwanted immunogenicity of therapeutic proteins arises through the combination of many factors, with the route of administration considered a significant contributor. Contrary to historic data on vaccine delivery, analysis of various therap...
Comparative Study
Journal of immunotoxicology. 2025 Dec;22(1):2537408. DOI:10.1080/1547691X.2025.2537408 2025
Evaluating impacts of the trichloroethylene metabolite S-(1,2-dichlorovyinyl)-L-cysteine on transcriptomic responses and cytokine release in a macrophage model: implications for pregnancy outcomes [0.03%]
三氯乙烯代谢产物S-（1,2-二氯乙烯基）-L-半胱氨酸对母细胞转录组学反应和细胞因子释放的影响：对妊娠结局的启示
Annella Benjamin,Erica Boldenow,Sammy Jaber et al.
Annella Benjamin et al.
Trichloroethylene (TCE) is a volatile synthetic chemical used in various industrial processes like metal degreasing. Large amounts of TCE have been released into the environment. Exposure to TCE can occur through routes, such as inhalation ...