Comprehensive review of avobenzone (butyl methoxydibenzoylmethane) toxicology data and human exposure assessment for personal care products [0.03%]
伞花烃茋甲烷（丁基甲氧基二苯甲酰基甲烷）毒理学数据及个人护理产品中人体暴露评估综述
Kimberly G Norman,Lewis E Kaufman,Carl D&#x;Ruiz et al.
Kimberly G Norman et al.
A comprehensive review of existing toxicity and human exposure data for the ultraviolet filter avobenzone (butyl methoxydibenzoylmethane) was conducted to assess its safety as currently used in over-the-counter sunscreen formulations. Avobe...
Female reproductive toxicity after exposure to malathion or diazinon: a systematic review of rodent and human studies [0.03%]
马拉硫磷和敌敌畏暴露后啮齿类动物及人类的雌性生殖毒性：系统评价研究
Indiamara Guesser Barbosa,Virgínia Meneghini Lazzari,Gabriel Adan Araújo Leite
Indiamara Guesser Barbosa
Malathion and diazinon are pesticides widely used in agriculture as well as for domestic and veterinary purposes to control pests, such as scale insects, aphids, and fleas. However, these compounds may have harmful effects on the female gen...
Toxicological insights into hydrogen sulfide biology in Caenorhabditis elegans: detection, metabolism, and functional outcomes [0.03%]
利用秀丽隐杆线虫探讨氢硫化物生物学的毒理学见解：检测、代谢及功能结果
Bobo Yang,Michael Aschner,Rongzhu Lu
Bobo Yang
Hydrogen sulfide (H2S), while historically recognized as a poisonous substance, also serves as a gasotransmitter that mediates a wide spectrum of physiological processes across species and is involved in the mechanisms of various exogenous ...
Meta-analysis of the safety and efficacy of fresh frozen plasma exchange in the treatment of organophosphate pesticide poisoning [0.03%]
新鲜冰冻血浆置换治疗有机磷中毒的疗效和安全性meta分析研究
Binrong Cai,Xian Yu,Xiaoyan Xian et al.
Binrong Cai et al.
This study evaluates whether fresh frozen plasma (FFP) improves outcomes compared to conventional therapy alone in organophosphorus poisoning (OP). Relevant literature was searched in PubMed, Web of Science, Embase, Cochrane Library, CNKI, ...
In search of certainty beyond the cholinergic system: a systematic review of developmental chlorpyrifos exposure and neurotransmitter systems disruption in preclinical models [0.03%]
超越胆碱能系统的不确定性探索：发育氯毗草酯暴露和神经传递素系统破坏的预临床模型系统性评价
Cristian Perez-Fernandez,Diego Ruiz-Sobremazas,Mario Ruiz-Coca et al.
Cristian Perez-Fernandez et al.
Chlorpyrifos (CPF) is one of the most widely used pesticides globally, despite being strictly regulated and banned in several developed countries. It remains in use across many developing and underdeveloped nations. While its primary mechan...
In vitro human brain barrier models for studying thyroid hormone transport [0.03%]
甲状腺激素转运的研究用体外人脑屏障模型
Kim Heikamp,Timo Hamers,Ellen V S Hessel
Kim Heikamp
Early brain development is dependent on the supply of thyroid hormone (TH) to the fetal brain. Disruption of TH concentrations in early brain development is associated with lower IQ and delayed motor development in children. How TH system d...
Human biomonitoring and risks of hazardous occupational exposure to polycyclic aromatic hydrocarbons in wildland fires: a critical review [0.03%]
职业暴露于野火中多环芳烃危害的生物监测与风险：批判性综述
Rafael Araújo Silva,Elizeu Chiodi Pereira,Kelly Polido Kaneshiro Olympio et al.
Rafael Araújo Silva et al.
The increase in global temperatures associated with climate change has intensified the frequency, duration, and severity of wildfires, resulting in exposure to a range of hazardous compounds, including polycyclic aromatic hydrocarbons (PAHs...
Development and application of meta-analysis in environmental health research [0.03%]
环境健康研究中meta分析的开展与应用
Qingyuan Li,Xiaoxing Liang,Renjun Yang et al.
Qingyuan Li et al.
The Adverse Outcome Pathway (AOP) framework is a foundational approach in environmental pollutant research, encompassing the detrimental effects of pollutants across biological levels from molecules to populations. Toxicogenomics (TGx), whi...
European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides [0.03%]
欧洲食品安全局关于农药体内发育神经毒性研究的数据库
Iris Mangas,Eliana Spilioti,Andrea Terron et al.
Iris Mangas et al.
Current evidence on the prevalence of neurodevelopmental disorders has raised concerns over the environmental etiology for developmental neurotoxicity. As the use of standardized in vivo developmental neurotoxicity methods has been restrict...
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation [0.03%]
构成型雄烷受体(CAR)和过氧化物酶增殖激活受体α(PPARα)活化剂致啮齿动物肝肿瘤形成的致癌机制与人类无相关性：最新评价
Tomoya Yamada,Samuel M Cohen,Brian G Lake
Tomoya Yamada
Constitutive androstane receptor (CAR) activators have long been known to enhance hepatocellular carcinogenesis in rodents, with the prototypic chemical being phenobarbital (PB). This has raised an ongoing controversy for the past 50 years ...