Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549-586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome-proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation [0.03%]
关于C.R. Wolf教授等人关于活化构成性安雄酮受体(CAR)和过氧化物酶增殖激活受体α(PPARα)的啮齿动物肝肿瘤形成的机制与人类致癌风险无关的评论的回复:最新评价
Tomoya Yamada,Samuel M Cohen,Brian G Lake
Tomoya Yamada
Letter to the editor regarding the review article: Yamada T, Cohen SM, Lake BG. The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation. Crit Rev Toxicol. 2025;55( [0.03%]
致编辑的信:关于 Yamada T, Cohen SM, Lake BG. 的评论文章——构成性安雄酮受体(CAR)和过氧化物酶增殖激活受体α(PPARα)活化剂诱导啮齿类动物肝肿瘤形成的机制与人类致癌风险无关:更新的关键评估批判毒理学评论文章的回复
C Roland Wolf,Colin J Henderson,Michael Schwarz et al.
C Roland Wolf et al.
Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products [0.03%]
八氢松香醇毒理学数据及人体接触评估的全面回顾用于个人护理产品
Kimberly G Norman,Lewis E Kaufman,Peter Griem et al.
Kimberly G Norman et al.
A comprehensive review was conducted of existing toxicity and consumer exposure data for the ultraviolet (UV) filter octocrylene (2-ethylhexyl-2-cyano-3,3-diphenylacrylate) as currently used in over-the-counter sunscreen formulations. Octoc...
Response to letter to the editor on: "the use of canonical dose-response models for benchmark dose analysis of continuous toxicological data" [0.03%]
来信:“连续毒理学数据基准剂量分析的规范剂量反应模型应用”的答复
Wout Slob,Guangchao Chen,Martine I Bakker et al.
Wout Slob et al.
Letter to the Editor: Critical analysis of "The use of canonical dose-response models for benchmark dose analysis of continuous toxicological data" by Slob et al. (2025) [0.03%]
致编辑的信:对Slob等(2025)的“连续毒理学数据基准剂量分析中规范剂量反应模型的应用”的批判性分析
José Cortiñas Abrahantes,Efisio Solazzo,Marc Aerts et al.
José Cortiñas Abrahantes et al.
The IARC re-classification of talc carcinogenicity: a move in the wrong direction? [0.03%]
关于滑石粉致癌性的IARC重新分类:错误的方向?
Andrey A Korchevskiy,Ann G Wylie
Andrey A Korchevskiy
The paper explores a content of the recent International Agency for Research on Cancer (IARC) Monograph (Volume 136) where pure talc was reclassified from the Group 2B ("Possibly carcinogenic to humans") to the Group 2 A ("Probably carcinog...
A comparative toxicological and epidemiological evaluation of dioxins and PFAS chemicals [0.03%]
二噁英和PFAS化学物质的毒理学和流行病学比较评估
Dennis Paustenbach,Karmen Kissell,Aryatara Shakya
Dennis Paustenbach
Regulatory frameworks, informed by robust and transparent scientific evidence, can significantly benefit society when thoughtful and measured regulation is promulgated. However, regulations founded on incomplete or misinterpreted science of...
Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods [0.03%]
全氟和多氟烷基物质混合暴露的健康效应流行病学研究系统性回顾
Megan J Kemp,Krishanth Thoppe,Kylie Jones et al.
Megan J Kemp et al.
Per- and polyfluoroalkyl substances (PFAS) continue to be an emerging chemical class of concern due to their long half-lives in nature and in the human body. There have been many epidemiology studies published in the scientific literature o...
Comprehensive review of ensulizole toxicology data and human exposure assessment for personal care products [0.03%]
恩 sulizole毒理学数据及个人护理产品人体暴露评估的全面评审
Kimberly G Norman,Lewis E Kaufman,Peter Griem et al.
Kimberly G Norman et al.
A comprehensive review of existing toxicity and human exposure data for the ultraviolet filter ensulizole (2-phenylbenzimidazole-5-sulfonic acid) as currently used in over-the-counter sunscreen formulations was conducted. Authorized maximum...
Inventory of possible endocrine disrupting chemicals used in cosmetic products [0.03%]
化妆品产品中所使用的潜在内分泌干扰化学物质的清单
Manon C Bouwmeester,Gaby A M Eliesen,Jeroen L A Pennings et al.
Manon C Bouwmeester et al.
There is a concern on the safety of cosmetic ingredients and their endocrine-disrupting (ED) potential. Frequent use as well as the use of a diverse range of cosmetics pose a concern for a potential health risk via aggregate exposure to end...