An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma [0.03%]
不同种类石棉对肺癌和间皮瘤的未观察到有害作用水平报告更新评估
Evan M Beckett,Anders Abelmann,Benjamin Roberts et al.
Evan M Beckett et al.
This analysis updates two previous analyses that evaluated the exposure-response relationships for lung cancer and mesothelioma in chrysotile-exposed cohorts. We reviewed recently published studies, as well as updated information from previ...
Hepatotoxicity due to dietary supplements: state-of-the-art, gaps and perspectives [0.03%]
膳食补充剂引起的肝毒性：现状、不足与展望
Fernando Rivero-Pino,Alfredo G Casanova
Fernando Rivero-Pino
Food supplements are products intended to complement the normal diet and consist of concentrated sources of nutrients or other substances with a nutritional or physiological effect. Although they are generally considered safe if the manufac...
From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications [0.03%]
从培育到致癌：无烟烟草中亚硝胺及其他致癌物的形成及其致突变意义
Stephen B Stanfill,Stephen S Hecht,Andreas C Joerger et al.
Stephen B Stanfill et al.
Tobacco use is a major cause of preventable morbidity and mortality globally. Tobacco products, including smokeless tobacco (ST), generally contain tobacco-specific N-nitrosamines (TSNAs), such as N'-nitrosonornicotine (NNN) and 4-(methylni...
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review [0.03%]
角叉菜胶(E 407)/处理过的石花菜(E 407a)和羧甲基纤维素钠盐(E 466)对肠道不良影响的证据与假说：系统综述
Mirlinda Tahiri,Celine Johnsrud,Inger-Lise Steffensen
Mirlinda Tahiri
This scoping review provides an overview of publications reporting adverse effects on the intestines of the food additives carrageenan (CGN) (E 407)/processed Eucheuma seaweed (PES) (E 407a) and carboxymethylcellulose (CMC) (E 466). It incl...
Wells Utembe,Charlene Andraos,Mary Gulumian
Wells Utembe
The toxicity of engineered nanomaterials (ENMs) in vivo and in vitro has formed the basis of most studies. However, the toxicity of ENMs, particularly on the immune system, i.e. immunotoxicity, and their role in manipulating it, are less kn...
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents [0.03%]
马拉硫磷或敌敌畏暴露与雄性生殖毒性：对采用啮齿动物开展的研究的系统评价
Daniel Delorenzi Schons,Gabriel Adan Araújo Leite
Daniel Delorenzi Schons
Malathion and diazinon are pesticides commonly used in agriculture to avoid insects that damage crops; however, they may cause impairment to the male genital system of exposed humans. The present work carried out a systematic review of the ...
Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach [0.03%]
基于化学的手部消毒凝胶对儿童的毒性及其天然替代品的发展——一种计算方法研究
Toshika Mishra,Suneetha Vuppu
Toshika Mishra
The unintended exposure of children to hand sanitizers poses a high risk of potentially fatal complications. Skin irritation, dryness, cracking, peeling, hypoglycemia, apnea, and acidosis are examples of unintended consequences of hand sani...
Tomás A E Gabrielli
Tomás A E Gabrielli
Incapacitating agents are chemical weapons that produce a temporary disabling condition that persists for hours or days after exposure. Their main site of action is the central nervous system and includes substances that are considered depr...
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles [0.03%]
基于动物实验的肺部中性粒细胞增多症综述及中性粒细胞在呼吸细颗粒物所致肺损伤中的作用机制分析
Chiu-Wing Lam,Vincent Castranova,Kevin Driscoll et al.
Chiu-Wing Lam et al.
The mechanisms of particle-induced pathogenesis in the lung remain poorly understood. Neutrophilic inflammation and oxidative stress in the lung are hallmarks of toxicity. Some investigators have postulated that oxidative stress from partic...
The environment and male reproductive system: the potential role and underlying mechanisms of cadmium in testis cancer [0.03%]
环境与男性的生殖系统：镉潜在参与睾丸癌的作用及机制研究
Cristina de Angelis,Giacomo Galdiero,Davide Menafra et al.
Cristina de Angelis et al.
Cadmium is a known human carcinogen, and has been shown to profoundly affect male reproductive function, at multiple levels, by exerting both endocrine and non-endocrine actions. Nevertheless, the potential role of cadmium in the etiology o...