Systematic review of studies on exposure to arsenic in drinking water and cognitive and neurobehavioral effects [0.03%]
关于饮水砷暴露与认知和神经行为效应的系统评价研究
Paolo Boffetta,Luisa Sambati,Michele Sassano
Paolo Boffetta
An association between exposure to arsenic (As) and neurologic and behavioral effects has been reported in some studies, but no systematic review is available of the evidence linking As in drinking water and neurobehavioral effects after co...
Consideration of the variability in control tumor incidence data at the Ramazzini Institute in evaluating treatment-related effects following chemical exposure [0.03%]
在评估化学物质暴露后的治疗相关影响时,考虑Ramazzini研究所提供的控制肿瘤发生数据的变异性
Robinan Gentry,Tracy Greene,Holly Bartow et al.
Robinan Gentry et al.
The Ramazzini Institute (RI) has been conducting animal carcinogenicity studies for decades, many of which have been considered by authoritative bodies to determine potential carcinogenicity in humans. Unlike other laboratories, such as the...
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review [0.03%]
新烟碱类农药的非急性暴露,健康风险评估及证据整合的系统评价
Imen Benchikh,Kaddour Ziani,Antonio Gonzalez Mateos et al.
Imen Benchikh et al.
Neonicotinoid pesticides are utilized against an extensive range of insects. A growing body of evidence supports that these neuro-active insecticides are classified as toxicants in invertebrates. However, there is limited published data reg...
Procedural application of mode-of-action and human relevance analysis: styrene-induced lung tumors in mice [0.03%]
作用机制和人体相关性分析在苯乙烯诱导的小鼠肺肿瘤研究中的程序化应用
Evan A Frank,M E Bette Meek
Evan A Frank
Risk assessment of human health hazards has traditionally relied on experiments that use animal models. Although exposure studies in rats and mice are a major basis for determining risk in many cases, observations made in animals do not alw...
Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants [0.03%]
中草药或其它植物来源的吡咯里西啶生物碱所致肝毒性的诊断、毒性机制和解毒原理
Zhenlin Huang,Zeqi Wu,Xinnan Gu et al.
Zhenlin Huang et al.
Pyrrolizidine alkaloids (PAs) are one type of phytotoxins distributed in various plants, including many medicinal herbs. Many organs might suffer injuries from the intake of PAs, and the liver is the most susceptible one. The diagnosis, tox...
The skin sensitization adverse outcome pathway: exploring the role of mechanistic understanding for higher tier risk assessment [0.03%]
皮肤致敏不良结局路径:探究机理理解在高级风险评估中的作用
Maja Aleksic,Ramya Rajagopal,Renato de-Ávila et al.
Maja Aleksic et al.
For over a decade, the skin sensitization Adverse Outcome Pathway (AOP) has served as a useful framework for development of novel in chemico and in vitro assays for use in skin sensitization hazard and risk assessment. Since its establishme...
Michael W Duffel,Hans-Joachim Lehmler
Michael W Duffel
Polychlorinated biphenyls (PCBs) are persistent organic toxicants derived from legacy pollution sources and their formation as inadvertent byproducts of some current manufacturing processes. Metabolism of PCBs is often a critical component ...
Systematic review of epidemiological and toxicological evidence on health effects of fluoride in drinking water [0.03%]
关于饮用水中氟化物健康影响的流行病学和毒理学证据的系统回顾
注解:这里的"systematic review"翻译为了“系统回顾”,"epidemiological and toxicological evidence" 翻译为 “流行病学和毒理学证据”, "health effects of fluoride in drinking water" 翻译为“饮用水中氟化物健康影响”。最后一部分"ifany"原文未完全翻译,因为其含义在中文标题中不明确且不影响主要意思的传达。若需表达出“如果有的话”的含义,可以改为:“关于饮用水中氟化物可能产生的健康影响的流行病学和毒理学证据的系统回顾”。
Mohamed Kadry Taher,Franco Momoli,Jennifer Go et al.
Mohamed Kadry Taher et al.
Introduction: Fluoride is a naturally occurring substance that is also added to drinking water, dental hygiene products, and food supplements for preventing dental caries. Concerns have been raised about several other pot...
Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review [0.03%]
杀真菌剂作为人类神经性疾病发病风险因素的系统性回顾
Renata Sano Lini,Deborah Thais Palma Scanferla,Nadya Garcia de Oliveira et al.
Renata Sano Lini et al.
Although studies show that pesticides, especially insecticides, may be toxic to humans, publications on the neurological effects of fungicides are scarce. As fungicides are used widely in Brazil, it is necessary to gather evidence to suppor...
Grouping approaches based on structure alone are insufficient to conclude about toxicological properties-the example of monoamine-based chelates [0.03%]
仅基于结构的分组方法不足以得出毒理学性质的结论-以单胺类鳌合物为例
Josje H E Arts,Sina Bader,Steffen Bade
Josje H E Arts
Aminocarboxylic acid (monoamine-based) chelating agents such as GLDA, MGDA, NTA, and EDG are widely used in a variety of products and processes. In the European Union, based on the Green Deal and the Chemicals Strategy for Sustainability (C...