Functional bipartite invariance in mouse primary visual cortex receptive fields [0.03%]
小鼠初级视觉皮层感受野的功能双分支不变性
Zhiwei Ding,Dat Tran,Kayla Ponder et al.
Zhiwei Ding et al.
Sensory systems support generalization by representing features that persist under input variation; however, identifying the neuronal basis of these invariances remains difficult due to high-dimensional and nonlinear neural computations. He...
Hiroaki Tsukano,Michellee M Garcia,Pranathi R Dandu et al.
Hiroaki Tsukano et al.
Habituation is a crucial sensory filtering mechanism whose dysregulation can lead to a continuously intense world in disorders with hypersensitivity. Although habituation is often termed the simplest form of learning, its circuit mechanisms...
Convolutional neural network models describe the encoding subspace of local circuits in auditory cortex [0.03%]
卷积神经网络模型描述听觉皮层局部回路的编码子空间
Jereme C Wingert,Satyabrata Parida,Sam V Norman-Haignere et al.
Jereme C Wingert et al.
Convolutional neural networks (CNNs) provide powerful models of neural sensory encoding, but their complexity makes it difficult to discern computations that support their performance. Here, to address this limitation, we developed a linear...
Behavioral timescale synaptic plasticity: properties, elements and functions [0.03%]
行为时间尺度的突触可塑性：特征、构成与功能
Jeffrey C Magee
Jeffrey C Magee
Understanding how brains learn and remember remains among the most important challenges in science. Recent studies in the hippocampus implicate a new form of synaptic plasticity, named behavioral timescale synaptic plasticity (BTSP), in the...
Author Correction: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease [0.03%]
作者更正：血管周围细胞通过SPP1诱导小胶质细胞吞噬状态和阿尔茨海默病模型中的突触内吞作用
Sebastiaan De Schepper,Judy Z Ge,Annerieke Sierksma et al.
Sebastiaan De Schepper et al.
Published Erratum
Nature neuroscience. 2026 Feb 17. DOI:10.1038/s41593-025-02197-6 2026
Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos [0.03%]
自身免疫性神经炎症通过MIF核酸酶介导的parthanatos导致神经元死亡
Jackson W Mace,Sachin P Gadani,Matthew D Smith et al.
Jackson W Mace et al.
Central nervous system inflammation is implicated in neurodegeneration across several disorders, including multiple sclerosis (MS). While marked therapeutic progress has been made in preventing relapses in MS, primary neuroprotection in thi...
Building scalable neuroimaging programs across diverse human environments [0.03%]
跨不同人类环境构建可扩展的神经影像程序
Tara C Thiagarajan,Sr John-Mary Vianney,Shailender Swaminathan et al.
Tara C Thiagarajan et al.
Distinct radial glia subtypes regulate midbrain dopaminergic neuron development [0.03%]
不同类型的放射状胶质细胞调节中脑多巴胺能神经元的发育
Emilía Sif Ásgrímsdóttir,Luca Fusar Bassini,Ting Sun et al.
Emilía Sif Ásgrímsdóttir et al.
Understanding the development of midbrain dopaminergic (mesDA) neurons is essential for advancing cell replacement therapies for Parkinson's disease. In the developing ventral midbrain (VM), radial glia (Rgl) cells are the progenitors of me...
Michael Z Leonard,Erin S Calipari
Michael Z Leonard
Duration between rewards controls the rate of behavioral and dopaminergic learning [0.03%]
奖励间隔影响行为和多巴胺能学习速率
Dennis A Burke,Annie Taylor,Huijeong Jeong et al.
Dennis A Burke et al.
Learning the causes of rewards is crucial for survival. Cue-reward associative learning is controlled in the brain by mesolimbic dopamine. It is widely believed that dopamine drives learning by conveying a reward prediction error. Dopamine-...