Cortical regulation of collective social dynamics during environmental challenge [0.03%]
皮层在环境应激下对集体社交动态的调节作用
Tara Raam,Qin Li,Linfan Gu et al.
Tara Raam et al.
Animal groups often collectively coordinate their behavior to withstand environmental challenges, yet the neural circuitry underlying such collective social dynamics remains unclear. Here we show that groups of mice self-organize into huddl...
Reduced mediodorsal thalamus activity underlies aberrant belief dynamics in a genetic mouse model of schizophrenia [0.03%]
遗传性小鼠模型中异常信念动力学源于腹内侧丘脑活动降低
Tingting Zhou,Yi-Yun Ho,Nolan D Hartley et al.
Tingting Zhou et al.
Belief updating is thought to be impaired in schizophrenia, leading to delusions. The neural substrates underlying belief updating are unknown, in part due to a lack of appropriate animal models and behavior readouts. We generated mice bear...
Eric G Ceballos,Asa Farahani,Zhen-Qi Liu et al.
Eric G Ceballos et al.
Neuropeptides are functionally diverse signaling molecules in the brain, regulating a wide range of basal bodily and cognitive processes. Despite their importance, the distribution and function of neuropeptides in the human brain remains un...
Restoring rapid natural bimanual typing with a neuroprosthesis after paralysis [0.03%]
瘫痪后的神经假体辅助双手快速自然打字
Justin J Jude,Hadar Levi-Aharoni,Alexander J Acosta et al.
Justin J Jude et al.
Here, recognizing keyboard typing as a familiar, high information rate communication paradigm, we developed an intracortical brain-computer interface (iBCI) typing neuroprosthesis providing bimanual QWERTY keyboard functionality for people ...
Circuit response to neuromodulation characterized with simultaneous deep brain stimulation and precision neuroimaging in humans [0.03%]
结合深部脑刺激和高精度神经影像技术表征人脑中与神经调制有关的电路反应
Jianxun Ren,Changqing Jiang,Wei Zhang et al.
Jianxun Ren et al.
Deep brain stimulation (DBS) is an effective treatment for Parkinson's disease (PD) but its neural mechanisms remain poorly understood. A mechanistic understanding requires precise characterization of functional responses to various stimula...
Competitive interactions shape mammalian brain network dynamics and computation [0.03%]
竞争互作形塑哺乳动物大脑网络动态及计算
Andrea I Luppi,Yonatan Sanz Perl,Jakub Vohryzek et al.
Andrea I Luppi et al.
How does brain network architecture balance cooperation and competition between distributed circuits? Here we use computational whole-brain modeling to examine the dynamical and computational relevance of cooperative and competitive interac...
Deconstruction of a memory engram reveals distinct ensembles recruited at learning [0.03%]
记忆印迹的解构揭示了学习时募集的不同神经元簇
Clément Pouget,Flora Morier,Livia Autore et al.
Clément Pouget et al.
The mechanisms of associative memory formation, including which cells encode a memory and the timing of their engagement, remain poorly understood. By visualizing and tagging cells based on their calcium influx with unparalleled temporal pr...
Author Correction: Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos [0.03%]
作者更正：自身免疫性神经炎症通过MIF核酸酶介导的parthanatos导致神经元死亡
Jackson W Mace,Sachin P Gadani,Matthew D Smith et al.
Jackson W Mace et al.
Published Erratum
Nature neuroscience. 2026 Mar 10. DOI:10.1038/s41593-026-02246-8 2026
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis [0.03%]
持续的干扰素信号引起感觉神经元可塑性并在类风湿关节炎之前和期间导致疼痛
Jie Su,Ming-Dong Zhang,Jussi Kupari et al.
Jie Su et al.
Although inflammatory processes in rheumatoid arthritis have been described, mechanisms driving pain are poorly defined. Here, we used a multitude of approaches to uncover the neural basis and causes of inflammatory pain. We show in mice wi...
Neuronal tuning aligns dynamically with object and texture manifolds across the visual hierarchy [0.03%]
视觉层级中神经元调谐与物体和纹理流形动态对齐
Binxu Wang,Carlos R Ponce
Binxu Wang
Visual neurons respond to a vast range of images, from textures to objects, but the rules linking these responses remain unclear. Although tuning to simple features is well established in the primary visual cortex, this framework breaks dow...