Diversity and immune dynamics of choroid plexus macrophages are shaped by distinct developmental origins [0.03%]
视黄膜脉络丛巨噬细胞的多样性及免疫动态受不同发育起源的影响
Siling Du,Khai M Nguyen,Alina Ulezko Antonova et al.
Siling Du et al.
The choroid plexus forms a key barrier and signaling interface between the brain and peripheral circulation, yet its immune landscape remains incompletely understood. Using single-cell transcriptomics combined with lineage and spatial traci...
Pierre Le Merre,Katharina Heining,Marina Slashcheva et al.
Pierre Le Merre et al.
The intrinsic organization underlying the central cognitive role of the prefrontal cortex (PFC) is poorly understood. We approached organization by profiling the activity and spatial location of >24,000 neurons recorded in awake mice. High-...
Author Correction: Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development [0.03%]
作者更正：脉络丛分沁作用影响小鼠脑部发育期间脑脊液蛋白质组学变化
Ya&#x;el Courtney,Joshua P Head,Neil Dani et al.
Ya&#x;el Courtney et al.
Published Erratum
Nature neuroscience. 2026 Jan 15. DOI:10.1038/s41593-026-02203-5 2026
Martijn P van den Heuvel,Ilan Libedinsky,Sebastian Quiroz Monnens et al.
Martijn P van den Heuvel et al.
Lesion network mapping (LNM) is a neuroimaging framework that uses normative functional connectivity (FC) data to link heterogeneous brain lesions and functional alterations to brain networks implicated in neurological and psychiatric condi...
Neuropixels go ultra [0.03%]
超神经元像素技术
Luis A Mejia
Luis A Mejia
Henrietta Howells
Henrietta Howells
Composing behavior [0.03%]
行为创作
William P Olson
William P Olson
Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion [0.03%]
小鼠大脑发育的空间转录组学免疫图谱揭示了母体免疫激活和微生物群耗竭的影响
Bharti Kukreja,Shin Jeon,Wuxinhao Cao et al.
Bharti Kukreja et al.
Immune molecules and their cognate receptors are developmentally regulated in brain and dynamically expressed in the context of neurodevelopmental disorders. Despite the importance of immune molecules to brain wiring, a comprehensive map of...
CRISPR knockout screens reveal genes and pathways essential for neuronal differentiation and implicate PEDS1 in neurodevelopment [0.03%]
利用CRISPR敲除筛选发现神经元分化的关键基因和信号通路并鉴定PEDS1在神经发育中的作用
Alana Amelan,Stephan C Collins,Nadirah S Damseh et al.
Alana Amelan et al.
Neurodevelopmental disorders (NDDs) arise from disruptions in brain development, yet the underlying pathways remain incompletely understood. Here we demonstrate that genome-wide CRISPR knockout screens in mouse embryonic stem cells differen...