H5N1 from an infected dairy worker sheds light on viral transmission [0.03%]
感染家禽业从业者的H5N1病毒提供了有关病毒传播的新信息
Karen O&#x;Leary
Karen O&#x;Leary
Oncolytic immunotherapy with nivolumab in muscle-invasive bladder cancer: a phase 1b trial [0.03%]
肌层浸润性膀胱癌的溶瘤免疫疗法nivolumab：一项二期临床试验
Roger Li,Nancy Y Villa,Xiaoqing Yu et al.
Roger Li et al.
There is a critical unmet need for safe and efficacious neoadjuvant treatment for cisplatin-ineligible patients with muscle-invasive bladder cancer. Here we launched a phase 1b study using the combination of intravesical cretostimogene gren...
Collaboration between clinicians and vision-language models in radiology report generation [0.03%]
临床医生与视觉语言模型在放射学报告生成中的合作
Ryutaro Tanno,David G T Barrett,Andrew Sellergren et al.
Ryutaro Tanno et al.
Automated radiology report generation has the potential to improve patient care and reduce the workload of radiologists. However, the path toward real-world adoption has been stymied by the challenge of evaluating the clinical quality of ar...
A systematic review and meta-analysis of heat exposure impacts on maternal, fetal and neonatal health [0.03%]
一项关于高温暴露对孕产妇、胎儿和新生儿健康影响的系统评价和meta分析研究
Darshnika P Lakhoo,Nicholas Brink,Lebohang Radebe et al.
Darshnika P Lakhoo et al.
Climate Change has severe and wide-ranging health impacts, especially for vulnerable groups. Despite growing evidence of heat-associated adverse maternal and neonatal health outcomes, there remains a lack of synthesis quantifying associatio...
Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis [0.03%]
基于人工智能的病理学工具在代谢功能紊乱相关肝炎评分中的临床验证
Hanna Pulaski,Stephen A Harrison,Shraddha S Mehta et al.
Hanna Pulaski et al.
Metabolic dysfunction-associated steatohepatitis (MASH) is a major cause of liver-related morbidity and mortality, yet treatment options are limited. Manual scoring of liver biopsies, currently the gold standard for clinical trial enrollmen...
Karen O&#x;Leary
Karen O&#x;Leary
Karen O&#x;Leary
Karen O&#x;Leary
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features [0.03%]
涵盖临床病理特征的乳腺癌转移活检的多种模式单细胞及空间表达图谱
Johanna Klughammer,Daniel L Abravanel,Åsa Segerstolpe et al.
Johanna Klughammer et al.
Although metastatic disease is the leading cause of cancer-related deaths, its tumor microenvironment remains poorly characterized due to technical and biospecimen limitations. In this study, we assembled a multi-modal spatial and cellular ...