Johain R Ounadjela,Ke Zhang,Koseki J Kobayashi-Kirschvink et al.
Johain R Ounadjela et al.
Successful pregnancy relies directly on the placenta's complex, dynamic, gene-regulatory networks. Disruption of this vast collection of intercellular and intracellular programs leads to pregnancy complications and developmental defects. In...
Sam N Barnett,Ana-Maria Cujba,Lu Yang et al.
Sam N Barnett et al.
The human vascular system, comprising endothelial cells (ECs) and mural cells, covers a vast surface area in the body, providing a critical interface between blood and tissue environments. Functional differences exist across specific vascul...
Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial [0.03%]
葡萄糖激酶激活剂托扎司他治疗2型糖尿病的III期随机临床研究：有效性与安全性评估
Barry A Borlaug,Michael R Zile,Christopher M Kramer et al.
Barry A Borlaug et al.
Patients with obesity-related heart failure with preserved ejection fraction (HFpEF) display circulatory volume expansion and pressure overload contributing to cardiovascular-kidney end-organ damage. In the SUMMIT trial, patients with HFpEF...
Author Correction: Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial [0.03%]
作者更正：Duvelisib联合Romidepsin治疗复发/难治T细胞淋巴瘤：一项Ib/IIa期临床试验
Steven M Horwitz,Ajit J Nirmal,Jahan Rahman et al.
Steven M Horwitz et al.
Published Erratum
Nature medicine. 2024 Dec;30(12):3778. DOI:10.1038/s41591-024-03404-w 2024
Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections [0.03%]
中枢神经系统感染诊断的临床元基因组下一代测序检测7年表现分析
Patrick Benoit,Noah Brazer,Mikael de Lorenzi-Tognon et al.
Patrick Benoit et al.
Metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) is an agnostic method for broad-based diagnosis of central nervous system (CNS) infections. Here we analyzed the 7-year performance of clinical CSF mNGS testing of 4...
Jose Pérez-García,Gabriele Antonarelli,Maria Gion et al.
Jose Pérez-García et al.
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial [0.03%]
针对外周T细胞淋巴瘤的TRBC1-CAR T细胞疗法I/II期临床试验
Kate Cwynarski,Gloria Iacoboni,Eleni Tholouli et al.
Kate Cwynarski et al.
Relapsed/refractory peripheral T cell lymphomas (PTCLs) are aggressive tumors with a poor prognosis. Unlike B cell lymphomas, treatment of PTCL has not benefited from advances in immunotherapy. This is largely due to a lack of suitable targ...