The path to safe, equitable and sustainable dialysis provision for people with chronic kidney disease [0.03%]
通往安全、公平和可持续的透析治疗之路：慢性肾脏病患者接受透析治疗的现状与展望
Yot Teerawattananon,Kinanti Khansa Chavarina,Jeerath Phannajit et al.
Yot Teerawattananon et al.
Syarifah Liza Munira
Syarifah Liza Munira
The Translational Research and Innovation Laboratory (TRAIL) model for accelerating discovery through a shared institutional resource [0.03%]
基于共享机构资源的发现加速模型——转化研究与创新实验室（TRAIL）模式
Steven Bruzek,Grant Vestal,John Morrison et al.
Steven Bruzek et al.
Clinical genetic variation across Hispanic populations in the Mexican Biobank [0.03%]
墨西哥生物银行中跨越不同西班牙人种群的临床遗传变异
Carmina Barberena-Jonas,Santiago G Medina-Muñoz,Viankail Cedillo-Castelán et al.
Carmina Barberena-Jonas et al.
Genetic testing for specific alleles is often recommended based on an individual's ancestry. However, the frequency of pathogenic and pharmacogenomic alleles across different Hispanic groups has not been well characterized, and existing gui...
Holistic evaluation of large language models for medical tasks with MedHELM [0.03%]
基于MedHELM的大规模语言模型医学任务全面评估
Suhana Bedi,Hejie Cui,Miguel Fuentes et al.
Suhana Bedi et al.
While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. Here we introduce MedHELM, an extensible evaluat...
Kyungdeok Kim,Ben Title,Jonathan Kipnis
Kyungdeok Kim
An LLM chatbot to facilitate primary-to-specialist care transitions: a randomized controlled trial [0.03%]
一种用于促进初级到专科护理过渡的LLM聊天机器人：一项随机对照试验
Xinge Tao,Shuya Zhou,Kai Ding et al.
Xinge Tao et al.
Patient-facing large language models (LLMs) hold potential to streamline inefficient transitions from primary to specialist care. We developed the preassessment (PreA), an LLM chatbot co-designed with local stakeholders, to perform the gene...
Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial [0.03%]
增强疫苗接种后的奖赏中脑边缘通路活动和免疫反应：一项随机对照实验
Nitzan Lubianiker,Tamar Koren,Meshi Djerasi et al.
Nitzan Lubianiker et al.
Growing evidence points to a close neurophysiological link between brain and body. Recent rodent studies have shown that the dopaminergic mesolimbic pathway, which underlies expectations of positive outcomes, also modulates immune function....
Michael Lattke,Wee Leng Tan,Salil Kalarikkal Sukumaran et al.
Michael Lattke et al.
Down syndrome (DS), caused by trisomy of chromosome 21, is the leading genetic cause of intellectual disability, yet the mechanisms disrupting fetal brain development remain unclear. We performed single-cell transcriptomic and chromatin acc...