Andrew Marshall
Andrew Marshall
Building synthetic chromosomes one yeast at a time: insights from Sc2.0 [0.03%]
千“酵”凝聚，共创生命乐章——Sc2.0项目综述与展望
Paige E Erpf,Felix Meier,Roy S K Walker et al.
Paige E Erpf et al.
Michael Francisco
Michael Francisco
Mateo Aboy,Kathleen Liddell,Cristina Crespo et al.
Mateo Aboy et al.
2025: research in review [0.03%]
2025：回顾研究进展
Lisa Melton
Lisa Melton
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles [0.03%]
使用包膜工程病毒样颗粒对人造血干细胞和祖细胞进行体内基因编辑
Vladimir V Botchkarev Jr,Sean Harrington,Matteo Stoppato et al.
Vladimir V Botchkarev Jr et al.
Engineered virus-like particles (VLPs) are a promising technology for in vivo gene editing of human hematopoietic stem and progenitor cells (HSPCs). Here we design and test two different VLP envelopes for human HSPC editing in vitro and in ...
Mapping single-cell diploid chromatin fiber architectures using DAF-seq [0.03%]
利用DAF-seq绘制单细胞二倍体染色质纤维结构地图
Elliott G Swanson,Yizi Mao,Benjamin J Mallory et al.
Elliott G Swanson et al.
Gene regulation is orchestrated by the co-binding of proteins along chromosome-length chromatin fibers within single cells, yet the heterogeneity of this occupancy between haplotypes and cells remains poorly resolved in diploid organisms. H...