Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic [0.03%]
深度学习方法DeepSomatic改进多种测序技术的体细胞小变异检测准确性
Jimin Park,Daniel E Cook,Pi-Chuan Chang et al.
Jimin Park et al.
Somatic variant detection is an integral part of cancer genomics analysis. While most methods have focused on short-read sequencing, long-read technologies offer potential advantages in repeat mapping and variant phasing. We present DeepSom...
Predicting functions of uncharacterized gene products from microbial communities [0.03%]
预测微生物群落中未表征基因产物的功能
Yancong Zhang,Amrisha Bhosle,Sena Bae et al.
Yancong Zhang et al.
The majority of genes in microbial communities remain uncharacterized. Here we develop a method to infer putative function for microbial proteins at scale by assessing community-wide multiomics data. We predict high-confidence functions for...
Laura DeFrancesco
Laura DeFrancesco
LeDNA: a cut-and-build toolkit to democratize CRISPR gene editing technology education [0.03%]
LeDNA：剪切和构建工具包，使CRISPR基因编辑技术教育民主化
Guilherme E Kundlatsch,Alina S L Rodrigues,Vitória F B Zocca et al.
Guilherme E Kundlatsch et al.
Big pharma seduced by transcription factors again. What has changed? [0.03%]
大型药企再次被转录因子所吸引，这次有什么不同？
Cormac Sheridan
Cormac Sheridan