Stochastic models allow improved inference of microbiome interactions from time series data [0.03%]
基于时间序列数据的微生物组相互作用的随机模型推断改善方法
Román Zapién-Campos,Florence Bansept,Arne Traulsen
Román Zapién-Campos
How can we figure out how the different microbes interact within microbiomes? To combine theoretical models and experimental data, we often fit a deterministic model for the mean dynamics of a system to averaged data. However, in the averag...
Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila [0.03%]
转座子和卫星DNA的周转在短时间内驱动果蝇进化中的着丝粒重组
Cécile Courret,Lucas W Hemmer,Xiaolu Wei et al.
Cécile Courret et al.
Centromeres reside in rapidly evolving, repeat-rich genomic regions, despite their essential function in chromosome segregation. Across organisms, centromeres are rich in selfish genetic elements such as transposable elements and satellite ...
The human posterior parietal cortices orthogonalize the representation of different streams of information concurrently coded in visual working memory [0.03%]
人脑后顶叶皮层使视觉工作记忆中同时编码的不同信息流的表征正交化
Yaoda Xu
Yaoda Xu
The key to adaptive visual processing lies in the ability to maintain goal-directed visual representation in the face of distraction. In visual working memory (VWM), distraction may come from the coding of distractors or other concurrently ...
Correction: Dog-human vocal interactions match dogs' sensory-motor tuning [0.03%]
纠正：犬-人发声互动与犬的感觉-运动调节相匹配
Eloïse C Déaux,Théophane Piette,Florence Gaunet et al.
Eloïse C Déaux et al.
[This corrects the article DOI: 10.1371/journal.pbio.3002789.]. Copyright: © 2024 Déaux et al. This is an open access article distributed under the ter...
Published Erratum
PLoS biology. 2024 Nov 19;22(11):e3002923. DOI:10.1371/journal.pbio.3002923 2024
Thalamic spindles and Up states coordinate cortical and hippocampal co-ripples in humans [0.03%]
人类丘脑尖峰和向上状态协调皮层和海马同步锐波震荡现象
Charles W Dickey,Ilya A Verzhbinsky,Sophie Kajfez et al.
Charles W Dickey et al.
In the neocortex, ~90 Hz ripples couple to ~12 Hz sleep spindles on the ~1 Hz Down-to-Up state transition during non-rapid eye movement sleep. This conjunction of sleep waves is critical for the consolidation of memories into long-term stor...
Trajectories of human brain functional connectome maturation across the birth transition [0.03%]
人生命周期中大脑功能连接组的成熟轨迹穿越出生阶段
Lanxin Ji,Iris Menu,Amyn Majbri et al.
Lanxin Ji et al.
Understanding the sequence and timing of brain functional network development at the beginning of human life is critically important from both normative and clinical perspectives. Yet, we presently lack rigorous examination of the longitudi...
Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons [0.03%]
presynaptic cAMP-PKA 介导的突触前 AMPA 受体阳性囊泡池和通道-囊泡偶联在海马 mossy fiber 拟 boutons 的再组织中的作用
Olena Kim,Yuji Okamoto,Walter A Kaufmann et al.
Olena Kim et al.
It is widely believed that information storage in neuronal circuits involves nanoscopic structural changes at synapses, resulting in the formation of synaptic engrams. However, direct evidence for this hypothesis is lacking. To test this co...
Excess mortality of infected ectotherms induced by warming depends on pathogen kingdom and evolutionary history [0.03%]
感染升温诱导的变温动物过量死亡受病原体界和进化史的影响
Jingdi Li,Nele Guttmann,Georgia C Drew et al.
Jingdi Li et al.
Climate change is causing extreme heating events and can lead to more infectious disease outbreaks, putting species persistence at risk. The extent to which warming temperatures and infection may together impair host health is unclear. Usin...
Meta-Analysis
PLoS biology. 2024 Nov 18;22(11):e3002900. DOI:10.1371/journal.pbio.3002900 2024
Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion [0.03%]
驱动果蝇嗅觉记忆吸引和回避的多巴胺神经元具有不同的即时功能
Farhan Mohammad,Yishan Mai,Joses Ho et al.
Farhan Mohammad et al.
The brain must guide immediate responses to beneficial and harmful stimuli while simultaneously writing memories for future reference. While both immediate actions and reinforcement learning are instructed by dopamine, how dopaminergic syst...
Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens [0.03%]
特异性的代谢表型可以用于病原菌抗菌靶点的鉴定
Emma M Glass,Lillian R Dillard,Glynis L Kolling et al.
Emma M Glass et al.
Bacterial pathogens pose a major risk to human health, leading to tens of millions of deaths annually and significant global economic losses. While bacterial infections are typically treated with antibiotic regimens, there has been a rapid ...