Growth-density inversion in Escherichia coli reveals superlinear, not sublinear, and density dependence [0.03%]
大肠杆菌生长密度反转揭示了超线性而非亚线性的密度依赖关系
James A Orr,Kaleigh E Davis,Alicia H Williams et al.
James A Orr et al.
Density dependence is a core principle in ecology and evolution, and yet the shape of the relationship between per capita growth and population size remains contentious. Sublinear (decelerating) density dependence has been widely reported i...
The zinc-finger protein ZC3H10 suppresses type I interferon responses during viral infection by repressing interferon-stimulated gene promoters [0.03%]
锌指蛋白ZC3H10通过抑制I型干扰素刺激基因启动子的活性来抑制病毒感染过程中的I型干扰素反应
Xiaojing Dong,Xiaoyan Zuo,Xia Xiao et al.
Xiaojing Dong et al.
Type I interferons (IFNs) play a central role in antiviral immunity by activating the JAK-STAT signaling pathway to induce interferon-stimulated genes (ISGs). Precise regulation of this response is critical to avoid pathological inflammatio...
Competing speech streams are simultaneously represented in the human cortex during attention switching [0.03%]
注意转换过程中竞争的语音流在人类大脑皮层中同时得到表征
Sara Carta,Emina Aličković,Johannes Zaar et al.
Sara Carta et al.
Successful speech communication in multi-talker scenarios requires a skillful combination of sustained attention and rapid attention switching. While the neurophysiology literature offers detailed insights into the neural underpinnings of s...
The G-force in the genome: Unknowns on the functional flairs of DNA G-quadruplexes [0.03%]
基因组中的G力：DNA G-四链体功能特性的未知数
Irene Gallina,Sara N Richter
Irene Gallina
Alternative DNA secondary structures known as G-quadruplexes (G4s) form across all kingdoms of life, regulating transcription, telomere stability, and genome maintenance. Although many putative G4-forming sequences are predicted to exist, i...
Peroxisomal import is circadian in glia and regulates sleep and lipid metabolism [0.03%]
过氧化物酶体输入具有昼夜节律性，在胶质细胞中对睡眠和脂质代谢进行调节
Anurag Das,Irma Magaly Rivas-Serna,Ankur Kumar et al.
Anurag Das et al.
Peroxisomes are critical organelles that detoxify cellular waste while also catabolizing and anabolizing lipids. How peroxisomes coordinate protein import and support metabolic functions across complex tissues and timescales remains poorly ...
Neurons generated shortly after birth encode the scent of early-life happiness [0.03%]
出生不久后生成的神经元编码早期生活的幸福气味
Chloé Guillaume,Elisa Galliano
Chloé Guillaume
Smells linked to joyful childhood events trigger vivid memories in adulthood, yet the mechanism behind their formation has remained elusive. A new PLOS Biology study shows that neurons generated around birth play a key role in encoding thes...
Dachsous-Fat signaling shapes the Drosophila wing through mechanical forces [0.03%]
Dachsous-Fat信号通过机械力塑造果蝇翅翼
Bipin Kumar Tripathi,Zhenru Zhou,Kenneth D Irvine
Bipin Kumar Tripathi
Proper organ shape is critical for function. The Drosophila wing normally adopts an elongated shape, but mutations in the Dachsous-Fat pathway result in rounder wings. The mechanism by which this occurs has remained unclear. Here, we show t...
Flight style and metabolism shape the tempo of genome evolution in birds [0.03%]
飞行方式和代谢模式影响鸟类基因组演化速率
Yanzhu Ji,Lei Wu,Dongming Li et al.
Yanzhu Ji et al.
As a hallmark of avian ecological innovation, powered flight has fundamentally shaped diverse aspects of birds. The energy demand of flight may have mutagenic impacts on genomes, influencing how fast genomes evolve. However, the relationshi...
Realistic monkey body animation reveals an uncanny valley in macaque body perception [0.03%]
逼真的猴子身体动画揭示了猕猴身体感知中的隐忧谷现象
Lucas M Martini,Anna Bognár,Rufin Vogels et al.
Lucas M Martini et al.
Social interactions are essential for survival in primates, relying on both facial expressions and body signals. The accurate characterization of these signals is critical for understanding the neurocomputational mechanisms underlying socia...
Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system [0.03%]
积极的早期生活嗅觉记忆根植于嗅球并触发超出嗅觉系统的广泛变化
Jules Dejou,Anna Athanassi,Théo Brunel et al.
Jules Dejou et al.
Olfactory childhood memories are particularly important for forming one's identity. However, we don't know how they exert their privileged influence and shape brain structure. To address this, we modeled childhood olfactory memory in mice b...