BehaveAI enables rapid detection and classification of objects and behavior from motion [0.03%]
BehaveAI使运动中的物体和行为的快速检测及分类成为可能
Jolyon Troscianko,Thomas A O&#x;Shea-Wheller,James A M Galloway et al.
Jolyon Troscianko et al.
Here we introduce BehaveAI, a biologically inspired video analysis framework that integrates static and motion information through a novel color-from-motion encoding strategy. This method translates object movement-direction, speed, and acc...
Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in Caenorhabditis elegans [0.03%]
转录组和染色质可及性分析揭示了Caenorhabditis elegans热休米斯的新调节因子
Hsin-Yun Chang,Sarah E McMurry,Sicheng Ma et al.
Hsin-Yun Chang et al.
Heat hormesis describes the beneficial adaptations resulting from transient exposure to mild heat stress, which enhances stress resilience and promotes healthy aging. While heat hormesis is widely observed, much remains to be learned about ...
CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferred [0.03%]
CRISPR-Cas在质粒竞争中具有优势，但其水平转移会受到竞争者毒素-抗毒素活性的限制
David Sünderhauf,Jahn R Ringger,Leighton J Payne et al.
David Sünderhauf et al.
Bacteria can encode dozens of different immune systems that protect them from infection by mobile genetic elements (MGEs). MGEs themselves may also carry immune systems, such as CRISPR-Cas, to target competitor MGEs. It is unclear when this...
Iridophore apoptosis mediates socially-regulated developmental color pattern plasticity in an anemonefish [0.03%]
群居调控拟态章鱼幼鱼体色变化的机制研究
Laurie J Mitchell,Saori Miura,Youjung Han et al.
Laurie J Mitchell et al.
Understanding the developmental basis of phenotypic plasticity is key to unraveling the origins of biodiversity. In coral reef fishes, color pattern changes during ontogeny can serve adaptive functions, yet the mechanisms and ecological con...
Neurofilament light chain may serve as a cross-species blood biomarker to assess aging and predict mortality [0.03%]
神经丝轻链可能是一种跨物种血液生物标志物，可用于评估衰老和预测死亡率
Carina Bergmann,Lisa M Häsler,Marius Lambert et al.
Carina Bergmann et al.
Blood levels of neurofilament light chain (NfL) increase with age in healthy humans and have been shown to predict all-cause human mortality. To determine whether this relationship is conserved across species, we analyzed NfL in the blood o...
Metabolic modeling reveals determinants of prebiotic and probiotic treatment efficacy across multiple human intervention trials [0.03%]
代谢建模揭示了多种人体干预试验中益生元和益生菌治疗有效性的决定因素
Nick Quinn-Bohmann,Alex V Carr,Sean M Gibbons
Nick Quinn-Bohmann
Prebiotic, probiotic, and combined (synbiotic) interventions often show variable outcomes across individuals, driven by complex interactions between introduced biotics, the endogenous microbiota, and the host diet. Predicting individual-spe...
Light intensity and opsin sensitivity shape the morphology of cone photoreceptor outer segments [0.03%]
光照强度和视蛋白敏感性塑造椎光受体外节形态
Jingjin Xu,Zihan Chang,Wei Deng et al.
Jingjin Xu et al.
Regulation of neural cell morphology remains a fundamental question in neuroscience. Photoreceptor cells, a specialized class of neurons capable of initiating the phototransduction cascade, exhibit distinct structural and morphological char...
Comparative gene annotation and orthology assignments across 301 species of Drosophilidae [0.03%]
301种果蝇科物种的基因注释及直系同源识别
Pankaj Dhakad,Bernard Y Kim,Dmitri A Petrov et al.
Pankaj Dhakad et al.
High-quality genome annotations are essential if we are to address central questions in comparative genomics, such as the origin of new genes, the drivers of genome size variation, and the evolutionary forces shaping gene content and struct...
Comparative Study
PLoS biology. 2026 Feb 18;24(2):e3003663. DOI:10.1371/journal.pbio.3003663 2026
DRfold2 is a deep learning-based tool that enables efficient and accurate RNA structure prediction [0.03%]
一种基于深度学习的高效准确RNA结构预测工具DRFold2
Yang Li,Chenjie Feng,Xi Zhang et al.
Yang Li et al.
RNA structures are essential for understanding their biological functions and developing RNA-targeted therapeutics. However, accurate RNA structure prediction from sequence remains a crucial challenge. We introduce DRfold2, a deep learning ...
Could targeting viruses be a new hope against neurodegenerative diseases? [0.03%]
靶向病毒会是治疗神经退行性疾病的新希望吗？
Karin M Danzer,Konstantin M J Sparrer
Karin M Danzer
Despite decades of intensive research, our current approaches to treating neurodegenerative diseases only slow down the seemingly inevitable. Could recent data associating vaccinations with reduced risk of dementia offer an unexpected beaco...