How I Approach Fertility Discussions in Pediatric, Adolescent, and Young Adult Patients With Cancer Predisposition Syndromes [0.03%]
我对患有癌症易感综合症的儿科、青少年和年轻成人患者的生育问题的处理方法
Urania Dagalakis,Kriti Kumar
Urania Dagalakis
Cancer predisposition syndromes (CPS) are identified in up to 20% of pediatric cancers and create dual fertility concerns: gonadotoxicity from therapy and heritable transmission risk. We present a practical framework to embed fertility coun...
Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor-Specific Outcomes in Adolescent and Young Adult Patients [0.03%]
儿童骨肉瘤治疗后患者的身心功能状况：青少年和年轻成人患者的一般情况及幸存者特定指标
Hinke van der Hoek,Heleen Maurice-Stam,Laura R Beek et al.
Hinke van der Hoek et al.
Background: Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body-altering treatment. This cross-sectional study aimed to evaluate gen...
How Clinicians Manage Sleep During Inpatient Hospitalization Following Pediatric Hematopoietic Stem Cell Transplantation [0.03%]
儿童造血干细胞移植后住院期间临床医生如何管理睡眠问题
Lydia Chevalier,Eva Robinson,Edie Weller et al.
Lydia Chevalier et al.
Although pediatric hematopoietic stem cell transplantation (HSCT) patients often experience sleep disruptions during hospitalization, no clinical guidelines exist for how to manage their sleep. We sought to learn how clinicians approach inp...
Recurrent Hypoglycemia Following Asparaginase Therapy for Lymphoid Malignancies in Childhood: The Texas Children's Hospital Experience [0.03%]
童年期治疗淋巴系统恶性肿瘤的阿斯帕庚酶后的反复低血糖发作：得克萨斯儿童医院的经验报告
Manal Y Tantoush,Alfonso Hoyos-Martinez,Michael E Scheurer et al.
Manal Y Tantoush et al.
Background: Hypoglycemia is a rarely reported complication of asparaginase (ASP) therapy in children with acute lymphoblastic leukemia/lymphoma (ALL/LLy). We sought to identify risk factors and outcomes among patients wit...
SIOP Standards Framework for Pediatric Oncology Units in Low- and Middle-Income Countries [0.03%]
低收入和中等收入国家儿童肿瘤科病房的SIOP标准框架
Ramandeep Singh Arora,Alan Davidson,Gloria Gonzalez et al.
Ramandeep Singh Arora et al.
Although standards exist for pediatric oncology units (POUs) in high-income countries, their applicability in low- and middle-income countries (LMICs) remains limited. Therefore, SIOP led a multidisciplinary global expert group to develop a...
Wearable Sleep Monitoring in Pediatric Acute Lymphoblastic Leukemia: Associations With Subjective Sleep Ratings and Neurocognitive Functioning [0.03%]
急性淋巴细胞白血病患儿的可穿戴睡眠监测与主观睡眠评分和神经认知功能的关系
Kathy Ruble,Rachel Northrup,Tomer Nusinov et al.
Kathy Ruble et al.
Background: Sleep disturbances are associated with increased fatigue, reduced quality of life, and neurocognitive dysfunction and have emerged as a common complication among pediatric cancer survivors. Sleep disturbances ...
Left Wilms Tumor With Bilateral Renal Vein and Inferior Vena Cava Thrombus [0.03%]
左肾母细胞瘤伴双侧肾静脉和下腔静脉瘤栓
YiWei Fang,Xinxuan Hu,Yang Yang et al.
YiWei Fang et al.
CO2 Laser Matrixectomy for Refractory MEK Inhibitor-Induced Paronychia in Children: A Case Series [0.03%]
用于治疗儿童难治性MEK抑制剂所致甲沟炎的二氧化碳点阵激光矩阵消融术：系列病例报道
Rivka Friedland,Yehonatan Noyman,Assi Levi et al.
Rivka Friedland et al.
Paronychia is a frequent cutaneous adverse event associated with MEK inhibitor therapy and may significantly impair quality of life and compromise treatment adherence. Treatment is usually medical, with poor and unsustained results. We retr...
Personalized Zebrafish Models for Fusion-Positive Pediatric Sarcomas [0.03%]
儿童肉瘤个性化斑马鱼模型及其在融合基因阳性肉瘤中的应用
Lisa H Hall,Emma N Harrison,Genevieve C Kendall
Lisa H Hall
Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinic...
Cyclosporine Stabilized the Hemoglobin Level in Children With Novel Compound Heterozygous Mutations in the LIG1 Gene: A Single Case Report [0.03%]
环孢素稳定了新型LIG1基因复合杂合突变患儿血红蛋白水平：病例报告
Shiwen Hu,Yanhe Wang,Haoyu Xie et al.
Shiwen Hu et al.