Rafael Moisan,Lydie Da Costa,Ludivine David Nguyen et al.
Rafael Moisan et al.
Diamond-Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain-of-function mutations in TP53 have been identified as a novel cause of Diamond-Blackfan anemia. We repo...
Blinatumomab Utilization in Pediatric B-Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West [0.03%]
Angela Parra Del Riego,Kellee Parker,William C Thomsen et al.
Angela Parra Del Riego et al.
Background: Blinatumomab is a bispecific T-cell engager approved for the treatment of pediatric B-cell acute lymphoblastic leukemia (B-ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource u...
Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk [0.03%]
Alannah R Srsich,Manali Zope,Peter M Fantozzi et al.
Alannah R Srsich et al.
Background: This study investigated how neighborhood-level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CT...
Functional Characterisation of a Novel RUNX1::ZNF777 Fusion in Biologically Aggressive Paediatric Acute Myeloid Leukaemia [0.03%]
Anna OSullivan,Luke Jones,Luis Iglesias-Martinez et al.
Anna OSullivan et al.
Two Faces of NOTCH1 in Childhood Lymphoblastic T-Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations [0.03%]
Marie C Heider,Amelie Alfert,Marc Hotfilder et al.
Marie C Heider et al.
In pediatric patients, T-cell lymphoblastic lymphoma (T-LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T-cell acute lymphoblastic leukemia (T-ALL) treatm...
'They Need to Hear You Say It': Healthcare Professionals' Perspectives on Barriers and Enablers to End-of-Life Discussions With Adolescents and Young Adults With Cancer [0.03%]
Justine Lee,Holly Evans,Claire E Wakefield et al.
Justine Lee et al.
End-of-life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the 'Difficult Discussions' study, focused on palliative care and advance care planni...
Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams [0.03%]
Leeat Granek,Lori Wiener,Stephanie Veldhuijzen van Zanten et al.
Leeat Granek et al.
Background: Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in ho...
Anterior Component Separation With Biologic Mesh for Reconstruction After Abdominal Wall Ewing Sarcoma Resection in an 18-Year-Old Male [0.03%]
David Y Chen,Annie Talbot,Jenny L Stevens et al.
David Y Chen et al.
Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium [0.03%]
Emily J Mason,John P Woodhouse,Joanna S Yi et al.
Emily J Mason et al.
Treatment-associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL a...
Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study [0.03%]
Anna Maria Markarian,Robert U Newton,Dennis R Taaffe et al.
Anna Maria Markarian et al.
Background: Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long-term health. Integrative neuromuscular training (INT), a mult...