Cup-Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation [0.03%]
杯状细胞核是DUX4/ERG急性淋巴细胞白血病的标志，揭示了细胞质线粒体积累的现象
Chloé Arfeuille,Hugo Roux,Odile Fenneteau et al.
Chloé Arfeuille et al.
Cup-like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial...
Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline [0.03%]
儿童肿瘤组放射治疗学科儿科放疗模拟规范报告
Parham Alaei,Stephen Mihalcik,Sujith Baliga et al.
Parham Alaei et al.
Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened...
Radiographic Brain Injury Following Proton Beam Therapy in Pediatric Medulloblastoma: Associations With Treatment Intensity and High-Dose Chemotherapy [0.03%]
质子刀治疗儿童髓母细胞瘤后的放射性脑损伤与高剂量化学疗法的关系及其对病情的影响
Suguru Uemura,Yusuke Demizu,Atsufumi Kawamura et al.
Suguru Uemura et al.
Background: Proton beam therapy (PBT) is increasingly used to treat pediatric medulloblastoma due to its favorable dose distribution and potential to mitigate late toxicity. However, concerns regarding radiation-induced c...
Improving Physical Activity Behaviors Among Childhood Cancer Survivors Through an Educational Intervention: A Mixed-Methods Pre-Post Study [0.03%]
通过教育干预提高儿童癌症幸存者身体活动行为的混合方法前后研究
Jiaoyang Cai,Yin Ting Cheung,Jiajia Zheng et al.
Jiaoyang Cai et al.
Background: Childhood cancer survivors (CCS) are at increased risk of long-term cardiopulmonary and functional complications, but physical activity participation remains low. Scalable, evidence-based interventions integra...
Correlation Between Kidney Size and Lean Body Mass in Survivors of Childhood and Young Adult Acute Lymphoblastic Leukemia [0.03%]
儿童及年轻成人急性淋巴细胞白血病幸存者肾脏体积与去脂体重的相关性研究
Elina Eriksson Wikberg,Ida Maria Schmidt,Cornelis Jan Pronk et al.
Elina Eriksson Wikberg et al.
Background: Survivors of acute lymphoblastic leukemia (ALL) have reduced lean body mass compared with the general population. In healthy children, an association between lean body mass and kidney size has been reported, w...
Transient Amegakaryocytic Thrombocytopenia With Congenital CMV: Neonatal Long-Term Follow-Up [0.03%]
先天性巨细胞病毒感染引起的暂时性幼浆细胞型血小板减少症的新生儿长期随访结果
Xiaoya Wei,Mengchun Li,Yanfei Liu
Xiaoya Wei
DNA Methylation Profiling of Pediatric Ectomesenchymoma Supports Embryonal Rhabdomyosarcoma-Like Epigenetic Identity [0.03%]
儿童外间充质瘤的DNA甲基化谱分析支持胚胎性横纹肌肉瘤样的表观遗传特性
Caporalini Chiara,Gianluca Mattei,Anna Maria Buccoliero et al.
Caporalini Chiara et al.
Ectomesenchymoma is a rare, biphenotypic pediatric tumor combining rhabdomyoblastic and neuroectodermal differentiation. We characterize two novel cases through integrated genomics and the first report of genome-wide DNA methylation profili...
Targeted Busulfan Conditioning for Cord Blood Transplantation in Newborn-Screened Severe Combined Immunodeficiency [0.03%]
针对新生儿筛查出的重度联合免疫缺陷病进行脐带血移植的Busulfan预处理疗法
Kosuke Mizuno,Takashi Ishikawa,Takashi Kitazawa et al.
Kosuke Mizuno et al.
Suicidal Ideation and Attempts Among Youth With Sickle Cell Disease Seeking Acute Care [0.03%]
急性期求医的青少年镰状细胞病患者自杀意念和企图的相关因素分析
Tanvi Karkare,Joseph Stanek,Monica Stanwick et al.
Tanvi Karkare et al.
Suicidal ideation (SI) and suicidal attempt (SA) rates are rising among youth in the United States; however, research on SI/SA in youth with sickle cell disease (Y-SCD) remains limited. Using the Pediatric Health Information System, we exam...
Paraneoplastic Chronic Recurrent Multifocal Osteomyelitis-Like Bone Disease in Pediatric Hodgkin Lymphoma [0.03%]
儿童霍奇金淋巴瘤伴类慢性复发性多灶性骨髓炎的副肿瘤综合征
Melda Berber Hamamcı,Sonay İncesoy Özdemir,Gül Arga et al.
Melda Berber Hamamcı et al.