Clinical Heterogeneity and Long-Term Outcomes of Pediatric Gastrointestinal Stromal Tumors: A Series of Four Patients Highlighting SDH-Deficient and SDH-Intact Subtypes [0.03%]
儿童胃肠间质瘤的临床异质性和长期结局：四例SDH缺陷型和SDH完整型胃肠道间质瘤患者的病例系列分析
Hala Elfarraj,Maha Barbar,Iyad Sultan et al.
Hala Elfarraj et al.
Pediatric gastrointestinal stromal tumors (GISTs) are rare, often lacking KIT or platelet-derived growth factor receptor-alpha (PDGFRA) mutations and driven by succinate dehydrogenase (SDH) deficiency. We report four pediatric patients (thr...
Bridging the Gap in Neuroblastoma Care: Consensus-Based Statements With Recommendations for Improved Patient and Caregiver Experiences [0.03%]
改善神经母细胞瘤患者和照顾者体验的共识声明及建议
Vickie Buenger,Joseph Bauer,Jennifer Diamond et al.
Vickie Buenger et al.
Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time-sensitive decisions. However, caregivers often feel unp...
Pediatric Cerebral Sinus Venous Thrombosis During the First Three Years of the SARS-CoV-2 Pandemic: A Multinational Case Series [0.03%]
SARS-CoV-2大流行初期三年内的儿科脑静脉窦血栓形成：多国病例系列报告
Marcela Torres,Allyson Schenk,Riten Kumar et al.
Marcela Torres et al.
Background: Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has been associated with thrombotic complications in adults and children. Cerebral sinovenous thrombosis (CSVT) has also been described in adults with...
Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP-WT-2001 Protocol in the SIOP-UK-CCLG and SIOP-GPOH Studies (2001-2022) [0.03%]
单侧肾母细胞瘤患者中的肾原基/肾blastomatosis与复发风险增加无关：SIOP-WT-2001方案在SIOP-UK-CCLG和SIOP-GPOH研究（2001-2022）中患者的分析
Gordan M Vujanić,Rhoikos Furtwängler,Tanzina Chowdhury et al.
Gordan M Vujanić et al.
Introduction: Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misun...
Health-Related Quality of Life and Symptom Burden in Pediatric Patients Receiving CAR T-Cell Therapy: A Prospective, Longitudinal Patient-Reported Outcomes Study [0.03%]
CAR-T细胞治疗的儿科患者的生命质量和症状负担：一项前瞻性纵向研究报告
Angela Steineck,Liyun Zhang,Amy Y Pan et al.
Angela Steineck et al.
Background: Chimeric antigen receptor (CAR) T-cell therapy has expanded rapidly as an investigational treatment for advanced cancers. Studies in acute lymphoblastic leukemia (ALL) suggest health-related quality of life (H...
Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341-Associated Cancer [0.03%]
儿童MN1::ZNF341相关癌症的临床、病理和分子特征分析
Thomas R W Oliver,Dyanne Rampling,Barbara Walkowiak et al.
Thomas R W Oliver et al.
A lethal round-cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radi...
Examining a Novel Neuropsychological Screening Tool in Pediatric Cancer Patients and Survivors [0.03%]
一种新型神经心理筛查工具在儿童癌症患者和存活者中应用的研究
Rachel S Werk,Shria K Haldipurkar,Jennifer L Reichek et al.
Rachel S Werk et al.
Background: Childhood cancer patients and survivors are vulnerable to neurocognitive deficits based on malignancy, treatment, and associated comorbidities. This study assessed a novel parent-report cognitive screening too...
Standardizing Fertility Preservation Counseling for Pediatric Hematology-Oncology and Transplant and Cellular Therapy Patients: A Quality Improvement Initiative [0.03%]
儿科血液肿瘤和移植细胞治疗患者的生育力保存咨询标准化：一项质量改进计划
Rachel Offenbacher,Emily F Stanford,Rachel Sklar et al.
Rachel Offenbacher et al.
Background: Infertility following gonadotoxic chemotherapy is among the most distressing late effects experienced by childhood cancer survivors, highlighting the importance of fertility preservation (FP) counseling at the...
Animal-Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland [0.03%]
德国、奥地利和瑞士儿科肿瘤学中动物辅助活动（治疗犬）的现状、实施及挑战的多中心调查研究
Jan-Marius Wedig,Birgit Burkhardt,Christof M Kramm et al.
Jan-Marius Wedig et al.
Background: Animal-assisted activities (AAAs) with therapy dogs have shown positive effects on patient well-being and quality of life in various areas of medicine, including pediatric oncology. However, research on this t...
Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients-A Single-Institution Retrospective Review [0.03%]
连续输注Blinatumomab治疗儿童患者的护理能力——单一机构回顾性分析
Julia M Hurley,Ryleigh Krueger,Kellie Joyce et al.
Julia M Hurley et al.
Blinatumomab, a CD19xCD3 bispecific T-cell engager, has become standard therapy for children with de novo B-cell acute lymphoblastic leukemia (B-ALL). This retrospective review describes the experience of blinatumomab administration in pedi...