Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso-Occlusive Pain Episodes [0.03%]
血栓症疾病住院患者的分泌型磷脂酶A2
Rawan Korman,Maria Yasmine,Dunia Hatabah et al.
Rawan Korman et al.
Background: Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso-occlusive pain epi...
Rheumatoid Factor-Positive Polyarthritis as a Complication of Dabrafenib and Trametinib in a Child With BRAF V600E-Mutated Pediatric Low-Grade Glioma [0.03%]
携带BRAF V600E突变的儿科低级别胶质瘤儿童接受达拉菲尼和曲美替尼治疗出现类风湿因子阳性的多关节炎并发症
Nahla Mobarak,Fatima Alanazi,Amani Albijadi et al.
Nahla Mobarak et al.
Drug Repurposing in Sickle Cell Disease: Evaluating Imatinib as a Therapeutic Candidate [0.03%]
药物再定位在镰状细胞病中的应用——评估伊马替尼作为治疗候选药物的可能性
Bijan Keikhaei,Daryush Purrahman,Najmeh Nameh Goshay Fard et al.
Bijan Keikhaei et al.
Sickle cell disease (SCD) is an inherited hemolytic hemoglobinopathy characterized by chronic hemolysis, vaso-occlusive pain crises, and progressive organ damage. Hydroxyurea, often combined with analgesics, remains a mainstay therapy, but ...
Methodological Quality and Content Analysis of Clinical Practice Guidelines for Fever Management in Children With Sickle Cell Disease [0.03%]
儿童镰状细胞病发热管理临床实践指南的方法学质量及内容分析
Elspeth Bittle,Tea Reljic,Ambuj Kumar et al.
Elspeth Bittle et al.
Infection/sepsis remains the number one cause of death among children under the age of 5 with sickle cell disease (SCD). Although clinical practice guidelines (CPGs) are an important tool for standardizing evidence-based care, the quantity ...
Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report [0.03%]
关于甲氨蝶呤神经毒性的易感性基因研究：减少急淋白血病医疗差异联盟研究报告
Rachel D Harris,Priya B Shetty,Olga A Taylor et al.
Rachel D Harris et al.
Background: Neurotoxicity is a rare, often dose-limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood....
Use of Ruxolitinib in Pediatric Polycythemia Vera: Expanding Indications Beyond Adult Paradigms? A Case Report [0.03%]
鲁索利替尼治疗儿童真性红细胞增多症：超越成人适应证？一例报道
Elie Cousin,Agathe Picard,Antoine Machet et al.
Elie Cousin et al.
Giulia Fiumana,Elena Arkhangelskaya,Barbara Cafferata et al.
Giulia Fiumana et al.
Access to Anticancer Drug Trials for Adolescents With Cancer in the United States [0.03%]
美国青少年抗癌药物试验的参与情况
Benjamin Grobman,David S Shulman,Vinayak Venkataraman et al.
Benjamin Grobman et al.
Background: Adolescents with cancer are generally underrepresented in clinical trials. The extent to which cancer drug clinical trials have become more age inclusive over time is not clear. ...
Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center [0.03%]
sickle细胞病治疗的改善缓解了由患病率增加引起的医疗利用：三级儿科中心的经验
Maude Cigna,Alexia Muresan,Estelle Lecluze et al.
Maude Cigna et al.
Background: Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect...
Psychosocial, Behavioral, and Clinical Correlates of Loneliness in Adolescent Cancer Survivors at the Transition off Treatment [0.03%]
青少年癌症生存者在结束治疗过渡期间的孤独感的心理社会、行为和临床特征
Nele Loecher,Kathryn Russell,Anna M Jones et al.
Nele Loecher et al.
Loneliness is common during adolescence, yet is poorly understood in adolescents with cancer. This study examined associations between loneliness and psychosocial, physical, and lifestyle factors. Among 49 adolescents ending treatment, 35.5...