Krista A Varady,Sofia Cienfuegos,Mark Ezpeleta et al.
Krista A Varady et al.
This review aims to summarize the effects of intermittent fasting on markers of cardiometabolic health in humans. All forms of fasting reviewed here-alternate-day fasting (ADF), the 5:2 diet, and time-restricted eating (TRE)-produced mild t...
Metabolic and Signaling Roles of Ketone Bodies in Health and Disease [0.03%]
酮体在机体健康和疾病过程中的代谢与信号转导作用
Patrycja Puchalska,Peter A Crawford
Patrycja Puchalska
Ketone bodies play significant roles in organismal energy homeostasis, serving as oxidative fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during states of low carbohydrate availability. Efforts to enhanc...
Diet-Host-Microbiota Interactions Shape Aryl Hydrocarbon Receptor Ligand Production to Modulate Intestinal Homeostasis [0.03%]
饮食-宿主-微生物群的相互作用形成芳烃受体配体生产以调节肠道内稳态
Huajun Han,Stephen Safe,Arul Jayaraman et al.
Huajun Han et al.
The aryl hydrocarbon receptor (AhR) is a ligand-activated basic-helix-loop-helix transcription factor that binds structurally diverse ligands and senses cues from environmental toxicants and physiologically relevant dietary/microbiota-deriv...
Rudi Balling,Patrick J Stover
Rudi Balling
Lucas J Osborn,Jan Claesen,J Mark Brown
Lucas J Osborn
Cardiometabolic disease (CMD) is a leading cause of death worldwide and encompasses the inflammatory metabolic disorders of obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. Flavonoids are poly...
Designing Relevant Preclinical Rodent Models for Studying Links Between Nutrition, Obesity, Metabolism, and Cancer [0.03%]
设计相关的临床前啮齿动物模型以研究营养、肥胖、代谢和癌症之间的联系
Elaine M Glenny,Michael F Coleman,Erin D Giles et al.
Elaine M Glenny et al.
Diet and nutrition are intricately related to cancer prevention, growth, and treatment response. Preclinical rodent models are a cornerstone to biomedical research and remain instrumental in our understanding of the relationship between can...
Faris M Zuraikat,Rebecca A Wood,Rocío Barragán et al.
Faris M Zuraikat et al.
Two factors intrinsic to health are diet and sleep. These two behaviors may well influence one another. Indeed, that insufficient sleep adversely impacts dietary intakes is well documented. On the other hand, diet may influence sleep via me...
The Influence of Front-of-Package Nutrition Labeling on Consumer Behavior and Product Reformulation [0.03%]
食品包装正面营养标签对消费者行为和产品配方改变的影响分析
Christina A Roberto,Shu Wen Ng,Montserrat Ganderats-Fuentes et al.
Christina A Roberto et al.
Countries worldwide have implemented mandatory or voluntary front-of-package nutrition labeling systems. We provide a narrative review of (a) real-world evaluations of front-of-package nutrition labels that analyze objective sales data and ...
The Roles of Cytoplasmic Lipid Droplets in Modulating Intestinal Uptake of Dietary Fat [0.03%]
胞浆脂滴调节肠细胞摄取膳食脂肪的作用机制研究进展
Alyssa S Zembroski,Changting Xiao,Kimberly K Buhman
Alyssa S Zembroski
Dietary fat absorption is required for health but also contributes to hyperlipidemia and metabolic disease when dysregulated. One step in the process of dietary fat absorption is the formation of cytoplasmic lipid droplets (CLDs) in small i...
Saurabh Mehta,Samantha L Huey,Daniel McDonald et al.
Saurabh Mehta et al.
The gut microbiome plays an integral role in health and disease, and diet is a major driver of its composition, diversity, and functional capacity. Given the dynamic development of the gut microbiome in infants and children, it is critical ...