Stephanie E McCalla,Anubhav Tripathi
Stephanie E McCalla
Diagnostic assays are an important part of health care, both in the clinic and in research laboratories. In addition to improving treatments and clinical outcomes, rapid and reliable diagnostics help track disease epidemiology, curb infecti...
Deformable medical image registration: setting the state of the art with discrete methods [0.03%]
可变形医学图像配准：用离散方法引领技术前沿
Ben Glocker,Aristeidis Sotiras,Nikos Komodakis et al.
Ben Glocker et al.
This review introduces a novel deformable image registration paradigm that exploits Markov random field formulation and powerful discrete optimization algorithms. We express deformable registration as a minimal cost graph problem, where nod...
Barclay Morrison rd,Benjamin S Elkin,Jean-Pierre Dollé et al.
Barclay Morrison rd et al.
In vitro models of traumatic brain injury (TBI) are helping elucidate the pathobiological mechanisms responsible for dysfunction and delayed cell death after mechanical stimulation of the brain. Researchers have identified compounds that ha...
Multiscale cancer modeling [0.03%]
多尺度癌症模型
Thomas S Deisboeck,Zhihui Wang,Paul Macklin et al.
Thomas S Deisboeck et al.
Simulating cancer behavior across multiple biological scales in space and time, i.e., multiscale cancer modeling, is increasingly being recognized as a powerful tool to refine hypotheses, focus experiments, and enable more accurate predicti...
MRI-guided nanorobotic systems for therapeutic and diagnostic applications [0.03%]
磁共振引导的纳米机器人系统在治疗和诊断中的应用
Panagiotis Vartholomeos,Matthieu Fruchard,Antoine Ferreira et al.
Panagiotis Vartholomeos et al.
This review presents the state of the art of magnetic resonance imaging (MRI)-guided nanorobotic systems that can perform diagnostic, curative, and reconstructive treatments in the human body at the cellular and subcellular levels in a cont...
Saiyong Zhu,Wanguo Wei,Sheng Ding
Saiyong Zhu
Stem cell technology holds great promises for the cures of devastating diseases, injuries, aging, and even cancers as it is applied in regenerative medicine. Recent breakthroughs in the development of induced pluripotent stem cell technique...
M B Esch,T L King,M L Shuler
M B Esch
High-quality, in vitro screening tools are essential in identifying promising compounds during drug development. Tests with currently used cell-based assays provide an indication of a compound's potential therapeutic benefits to the target ...
Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds [0.03%]
整体组织工程学：三维基质支架的脱细胞和再细胞化
Stephen F Badylak,Doris Taylor,Korkut Uygun
Stephen F Badylak
The definitive treatment for end-stage organ failure is orthotopic transplantation. However, the demand for transplantation far exceeds the number of available donor organs. A promising tissue-engineering/regenerative-medicine approach for ...
Artificial noses [0.03%]
人造鼻器官
Shannon E Stitzel,Matthew J Aernecke,David R Walt
Shannon E Stitzel
The mammalian olfactory system is able to detect many more odorants than the number of receptors it has by utilizing cross-reactive odorant receptors that generate unique response patterns for each odorant. Mimicking the mammalian system, a...
Marcus G Pandy,Thomas P Andriacchi
Marcus G Pandy
This review describes how computational modeling can be combined with noninvasive gait measurements to describe and explain muscle and joint function in human locomotion. Five muscles--the gluteus maximus, gluteus medius, vasti, soleus, and...