Objective Assessment of Surgical Technical Skill and Competency in the Operating Room [0.03%]
手术室外科技术技能和胜任力的客观评估
S Swaroop Vedula,Masaru Ishii,Gregory D Hager
S Swaroop Vedula
Training skillful and competent surgeons is critical to ensure high quality of care and to minimize disparities in access to effective care. Traditional models to train surgeons are being challenged by rapid advances in technology, an inten...
Epigenetic Regulation: A New Frontier for Biomedical Engineers [0.03%]
表观遗传调控： biomedical engineers的新的前沿领域
Zhen Chen,Shuai Li,Shankar Subramaniam et al.
Zhen Chen et al.
Gene expression in mammalian cells depends on the epigenetic status of the chromatin, including DNA methylation, histone modifications, promoter-enhancer interactions, and noncoding RNA-mediated regulation. The coordinated actions of these ...
Lifeng Yang,Sriram Venneti,Deepak Nagrath
Lifeng Yang
Glutamine is the most abundant circulating amino acid in blood and muscle and is critical for many fundamental cell functions in cancer cells, including synthesis of metabolites that maintain mitochondrial metabolism; generation of antioxid...
Dinggang Shen,Guorong Wu,Heung-Il Suk
Dinggang Shen
This review covers computer-assisted analysis of images in the field of medical imaging. Recent advances in machine learning, especially with regard to deep learning, are helping to identify, classify, and quantify patterns in medical image...
Assessing Cartilage Biomechanical Properties: Techniques for Evaluating the Functional Performance of Cartilage in Health and Disease [0.03%]
评估软骨生物力学性质：健康和疾病状态下评价软骨功能性能的技术
Benjamin A Lakin,Brian D Snyder,Mark W Grinstaff
Benjamin A Lakin
Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due to overloading. During joint articulation, hyaline cartilage must withstand high loads while maintaining low friction to prevent wear and tissue lo...
Sulfation of Glycosaminoglycans and Its Implications in Human Health and Disorders [0.03%]
糖胺聚糖硫酸化及其在人类健康和疾病中的作用
Diana Soares da Costa,Rui L Reis,Iva Pashkuleva
Diana Soares da Costa
Sulfation is a dynamic and complex posttranslational modification process. It can occur at various positions within the glycosaminoglycan (GAG) backbone and modulates extracellular signals such as cell-cell and cell-matrix interactions; dif...
Overcoming Immune Dysregulation with Immunoengineered Nanobiomaterials [0.03%]
具有免疫调控功能的纳米生物材料在免疫修复中的应用
Evan A Scott,Nicholas B Karabin,Punn Augsornworawat
Evan A Scott
The immune system is governed by an immensely complex network of cells and both intracellular and extracellular molecular factors. It must respond to an ever-growing number of biochemical and biophysical inputs by eliciting appropriate and ...
Emerging Themes in Image Informatics and Molecular Analysis for Digital Pathology [0.03%]
数字病理学中图像信息学和分子分析的新兴主题
Rohit Bhargava,Anant Madabhushi
Rohit Bhargava
Pathology is essential for research in disease and development, as well as for clinical decision making. For more than 100 years, pathology practice has involved analyzing images of stained, thin tissue sections by a trained human using an ...
Will Goth,John Lesicko,Michael S Sacks et al.
Will Goth et al.
Fibrous structures are an integral and dynamic feature of soft biological tissues that are directly related to the tissues' condition and function. A greater understanding of mechanical tissue behavior can be gained through quantitative ana...
Bobby Reddy,Eric Salm,Rashid Bashir
Bobby Reddy
As the future of health care diagnostics moves toward more portable and personalized techniques, there is immense potential to harness the power of electrical signals for biological sensing and diagnostic applications at the point of care. ...