Human Cerebellar Development and Transcriptomics: Implications for Neurodevelopmental Disorders [0.03%]
人脑小脑发育和转录组学：对神经发育障碍的启示
Parthiv Haldipur,Kathleen J Millen,Kimberly A Aldinger
Parthiv Haldipur
Developmental abnormalities of the cerebellum are among the most recognized structural brain malformations in human prenatal imaging. Yet reliable information regarding their cause in humans is sparse, and few outcome studies are available ...
Carla Taveggia,M Laura Feltri
Carla Taveggia
Schwann cells in the peripheral nervous system (PNS) are essential for the support and myelination of axons, ensuring fast and accurate communication between the central nervous system and the periphery. Schwann cells and related glia accom...
John R Lukens,Ukpong B Eyo
John R Lukens
Mounting evidence indicates that microglia, which are the resident immune cells of the brain, play critical roles in a diverse array of neurodevelopmental processes required for proper brain maturation and function. This evidence has ultima...
Considering Organismal Physiology in Laboratory Studies of Rodent Behavior [0.03%]
考虑有机体生理学在啮齿动物行为实验室研究中的作用
Patricia Rubio Arzola,Rebecca M Shansky
Patricia Rubio Arzola
Any experiment conducted in a rodent laboratory is done so against the backdrop of each animal's physiological state at the time of the experiment. This physiological state can be the product of multiple factors, both internal (e.g., animal...
Karolina Janacsek,Tanya M Evans,Mariann Kiss et al.
Karolina Janacsek et al.
Cognitive neuroscience has highlighted the cerebral cortex while often overlooking subcortical structures. This cortical proclivity is found in basic and translational research on many aspects of cognition, especially higher cognitive domai...
Roel G J Klein Wolterink,Glendon S Wu,Isaac M Chiu et al.
Roel G J Klein Wolterink et al.
Interactions between the nervous and immune systems were recognized long ago, but recent studies show that this crosstalk occurs more frequently than was previously appreciated. Moreover, technological advances have enabled the identificati...
Neuromodulation and Neurophysiology on the Timescale of Learning and Decision-Making [0.03%]
学习和决策时间尺度上的神经调制和神经生理学
Cooper D Grossman,Jeremiah Y Cohen
Cooper D Grossman
Nervous systems evolved to effectively navigate the dynamics of the environment to achieve their goals. One framework used to study this fundamental problem arose in the study of learning and decision-making. In this framework, the demands ...
Gregg A Castellucci,Frank H Guenther,Michael A Long
Gregg A Castellucci
Vocal communication is a critical feature of social interaction across species; however, the relation between such behavior in humans and nonhumans remains unclear. To enable comparative investigation of this topic, we review the literature...
Fluorescence Imaging of Neural Activity, Neurochemical Dynamics, and Drug-Specific Receptor Conformation with Genetically Encoded Sensors [0.03%]
基于遗传编码传感器的神经活动、神经化学动力学及药物特异性受体构象的荧光成像技术研究进展
Chunyang Dong,Yu Zheng,Kiran Long-Iyer et al.
Chunyang Dong et al.
Recent advances in fluorescence imaging permit large-scale recording of neural activity and dynamics of neurochemical release with unprecedented resolution in behaving animals. Calcium imaging with highly optimized genetically encoded indic...
Hidehiko K Inagaki,Susu Chen,Kayvon Daie et al.
Hidehiko K Inagaki et al.
The brain plans and executes volitional movements. The underlying patterns of neural population activity have been explored in the context of movements of the eyes, limbs, tongue, and head in nonhuman primates and rodents. How do networks o...