Striosomes and Matrisomes: Scaffolds for Dynamic Coupling of Volition and Action [0.03%]
纹状体和基质：意愿与行为动态耦合的支架
Ann M Graybiel,Ayano Matsushima
Ann M Graybiel
Striosomes form neurochemically specialized compartments of the striatum embedded in a large matrix made up of modules called matrisomes. Striosome-matrix architecture is multiplexed with the canonical direct-indirect organization of the st...
Sameer A Sheth,Helen S Mayberg
Sameer A Sheth
The field of stereotactic neurosurgery developed more than 70 years ago to address a therapy gap for patients with severe psychiatric disorders. In the decades since, it has matured tremendously, benefiting from advances in clinical and bas...
Neural Control of Sexually Dimorphic Social Behavior: Connecting Development to Adulthood [0.03%]
神经控制两性差异社交行为：连接发育与成年期
Margaret M McCarthy
Margaret M McCarthy
Rapid advances in the neural control of social behavior highlight the role of interconnected nodes engaged in differential information processing to generate behavior. Many innate social behaviors are essential to reproductive fitness and t...
Integration of Feedforward and Feedback Information Streams in the Modular Architecture of Mouse Visual Cortex [0.03%]
鼠标视觉皮层模块化结构中前馈和反馈信息流的整合
Andreas Burkhalter,Rinaldo D D&#x;Souza,Weiqing Ji et al.
Andreas Burkhalter et al.
Radial cell columns are a hallmark feature of cortical architecture in many mammalian species. It has long been held, based on the lack of orientation columns, that such functional units are absent in rodent primary visual cortex (V1). Thes...
James B Heald,Daniel M Wolpert,Máté Lengyel
James B Heald
Flexible behavior requires the creation, updating, and expression of memories to depend on context. While the neural underpinnings of each of these processes have been intensively studied, recent advances in computational modeling revealed ...
György Buzsáki,David Tingley
György Buzsáki
Examination of cognition has historically been approached from language and introspection. However, human language-dependent definitions ignore the evolutionary roots of brain mechanisms and constrain their study in experimental animals. We...
Neural Circuits for Emotion [0.03%]
情绪的神经环路
Meryl Malezieux,Alexandra S Klein,Nadine Gogolla
Meryl Malezieux
Emotions are fundamental to our experience and behavior, affecting and motivating all aspects of our lives. Scientists of various disciplines have been fascinated by emotions for centuries, yet even today vigorous debates abound about how t...
How Instructions, Learning, and Expectations Shape Pain and Neurobiological Responses [0.03%]
指导、学习和预期如何塑造疼痛及神经生物学反应
Lauren Y Atlas
Lauren Y Atlas
Treatment outcomes are strongly influenced by expectations, as evidenced by the placebo effect. Meta-analyses of clinical trials reveal that placebo effects are strongest in pain, indicating that psychosocial factors directly influence pain...
Dan Levy,Michael A Moskowitz
Dan Levy
Migraine is a complex neurovascular pain disorder linked to the meninges, a border tissue innervated by neuropeptide-containing primary afferent fibers chiefly from the trigeminal nerve. Electrical or mechanical stimulation of this nerve su...
Mohini Sengupta,Martha W Bagnall
Mohini Sengupta
The spinal cord is home to the intrinsic networks for locomotion. An animal in which the spinal cord has been fully severed from the brain can still produce rhythmic, patterned locomotor movements as long as some excitatory drive is provide...