Michael H Hastings,Marco Brancaccio,Maria F Gonzalez-Aponte et al.
Michael H Hastings et al.
This review explores the interface between circadian timekeeping and the regulation of brain function by astrocytes. Although astrocytes regulate neuronal activity across many time domains, their cell-autonomous circadian clocks exert a par...
Therapeutic Potential of PTBP1 Inhibition, If Any, Is Not Attributed to Glia-to-Neuron Conversion [0.03%]
PTBP1抑制的潜在治疗作用（如果有）不源于胶质细胞到神经元的转分化
Lei-Lei Wang,Chun-Li Zhang
Lei-Lei Wang
A holy grail of regenerative medicine is to replenish the cells that are lost due to disease. The adult mammalian central nervous system (CNS) has, however, largely lost such a regenerative ability. An emerging strategy for the generation o...
Guillermina López-Bendito,Mar Aníbal-Martínez,Francisco J Martini
Guillermina López-Bendito
Unimodal sensory loss leads to structural and functional changes in both deprived and nondeprived brain circuits. This process is broadly known as cross-modal plasticity. The evidence available indicates that cross-modal changes underlie th...
The Cerebellar Cortex [0.03%]
小脑皮质
Court Hull,Wade G Regehr
Court Hull
The cerebellar cortex is an important system for relating neural circuits and learning. Its promise reflects the longstanding idea that it contains simple, repeated circuit modules with only a few cell types and a single plasticity mechanis...
Theory of the Multiregional Neocortex: Large-Scale Neural Dynamics and Distributed Cognition [0.03%]
多区域新皮层理论：大规模神经动力学和分布式认知
Xiao-Jing Wang
Xiao-Jing Wang
The neocortex is a complex neurobiological system with many interacting regions. How these regions work together to subserve flexible behavior and cognition has become increasingly amenable to rigorous research. Here, I review recent experi...
Amir Rattner,Yanshu Wang,Jeremy Nathans
Amir Rattner
During development, the central nervous system (CNS) vasculature grows to precisely meet the metabolic demands of neurons and glia. In addition, the vast majority of the CNS vasculature acquires a unique set of molecular and cellular proper...
Liad Mudrik,Leon Y Deouell
Liad Mudrik
The extent to which we are affected by perceptual input of which we are unaware is widely debated. By measuring neural responses to sensory stimulation, neuroscientific data could complement behavioral results with valuable evidence. Here w...
Gabriel Montaldo,Alan Urban,Emilie Macé
Gabriel Montaldo
Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal resolution. fUS is capable of imaging head-fixed or freel...
Puja K Parekh,Shane B Johnson,Conor Liston
Puja K Parekh
Depression is an episodic form of mental illness characterized by mood state transitions with poorly understood neurobiological mechanisms. Antidepressants reverse the effects of stress and depression on synapse function, enhancing neurotra...
Rosemary C Challis,Sripriya Ravindra Kumar,Xinhong Chen et al.
Rosemary C Challis et al.
Recombinant adeno-associated viruses (AAVs) are commonly used gene delivery vehicles for neuroscience research. They have two engineerable features: the capsid (outer protein shell) and cargo (encapsulated genome). These features can be mod...