Linda H Kim,Detlef H Heck,Roy V Sillitoe
Linda H Kim
The cerebellum has a well-established role in controlling motor functions, including coordination, posture, and the learning of skilled movements. The mechanisms for how it carries out motor behavior remain under intense investigation. Inte...
Learning, Fast and Slow: Single- and Many-Shot Learning in the Hippocampus [0.03%]
快与慢的学习：海马体中的单示例学习和少数示例学习
Zhenrui Liao,Attila Losonczy
Zhenrui Liao
The hippocampus is critical for memory and spatial navigation. The ability to map novel environments, as well as more abstract conceptual relationships, is fundamental to the cognitive flexibility that humans and other animals require to su...
The Role of Retrotransposons and Endogenous Retroviruses in Age-Dependent Neurodegenerative Disorders [0.03%]
逆转录子和内源性逆转录病毒在线粒体年龄依赖性疾病相关神经退行性疾病中的作用
Bess Frost,Josh Dubnau
Bess Frost
Over 40% of the human genome is composed of retrotransposons, DNA species that hold the potential to replicate via an RNA intermediate and are evolutionarily related to retroviruses. Retrotransposons are most studied for their ability to ju...
Andrea Francesca M Salvador,Nora Abduljawad,Jonathan Kipnis
Andrea Francesca M Salvador
Since its recent discovery, the meningeal lymphatic system has reshaped our understanding of central nervous system (CNS) fluid exchange, waste clearance, immune cell trafficking, and immune privilege. Meningeal lymphatics have also been de...
Eloísa Herrera,Alain Chédotal,Carol Mason
Eloísa Herrera
Seeing in three dimensions is a major property of the visual system in mammals. The circuit underlying this property begins in the retina, from which retinal ganglion cells (RGCs) extend to the same or opposite side of the brain. RGC axons ...
From Blur to Brilliance: The Ascendance of Advanced Microscopy in Neuronal Cell Biology [0.03%]
从模糊到清晰：高级显微镜技术在神经细胞生物学中的崛起
Kirby R Campbell,Liam P Hallada,Yu-Shan Huang et al.
Kirby R Campbell et al.
The intricate network of the brain's neurons and synapses poses unparalleled challenges for research, distinct from other biological studies. This is particularly true when dissecting how neurons and their functional units work at a cell bi...
Dominic D Frank,Daniel J C Kronauer
Dominic D Frank
Ant physiology has been fashioned by 100 million years of social evolution. Ants perform many sophisticated social and collective behaviors yet possess nervous systems similar in schematic and scale to that of the fruit fly Drosophila melan...
Antoine Huet,Thomas Mager,Christian Gossler et al.
Antoine Huet et al.
The cochlear implant (CI) is considered the most successful neuroprosthesis as it enables speech comprehension in the majority of the million otherwise deaf patients. In hearing by electrical stimulation of the auditory nerve, the broad spr...
Circuit-Specific Deep Brain Stimulation Provides Insights into Movement Control [0.03%]
特定电路的深度脑刺激为运动控制提供了洞见
Aryn H Gittis,Roy V Sillitoe
Aryn H Gittis
Deep brain stimulation (DBS), a method in which electrical stimulation is delivered to specific areas of the brain, is an effective treatment for managing symptoms of a number of neurological and neuropsychiatric disorders. Clinical access ...
Georg B Keller,Philipp Sterzer
Georg B Keller
Predictive processing is a computational framework that aims to explain how the brain processes sensory information by making predictions about the environment and minimizing prediction errors. It can also be used to explain some of the key...