Ram Sanath-Kumar,Qin Liao,Zhongqing Ren et al.
Ram Sanath-Kumar et al.
Structural maintenance of chromosomes (SMC) complexes are conserved ATP-driven machines that organize, compact, and segregate genomes in all domains of life. Despite variation in subunit composition and regulation, all SMC complexes share a...
Isabel Sakarin,Julian P Maceren,Jessica C Seeliger
Isabel Sakarin
The mycobacterial cell envelope is a formidable barrier, regarded as one of the most chemically and structurally elaborate architectures in the Bacteria kingdom. Membrane remodeling, defined as changes in membrane lipid composition in respo...
Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors [0.03%]
基于结构的LuxR型群体感应受体分子机制新见解
Irene M Stoutland,Mai V Beauclaire,Mikael H Elias et al.
Irene M Stoutland et al.
Quorum sensing (QS) enables bacteria to coordinate collective behaviors in response to population density. LuxI/R QS systems, common among gram-negative bacteria, consist of a LuxI-type synthase that produces an N-acyl L-homoserine lactone ...
Structure and Function of the Type IX Secretion System for Protein Secretion and Cellular Motility [0.03%]
III型分泌系统蛋白分泌与细胞运动的结构和功能
Yaëlle Aouizerate,Thierry Doan,Eric Cascales
Yaëlle Aouizerate
The type IX secretion system (T9SS) is a Bacteroidota-specific multiprotein machine that supports a wide range of biological processes, from nutrient acquisition and surface modification to host interaction and gliding motility. T9SS effect...
Allen R Buskirk
Allen R Buskirk
Ribosome rescue pathways recycle the subunits from stalled ribosomes and target the aborted nascent peptide for degradation. Building upon seminal studies in eukaryotes, recent work in bacteria shows that rescue pathways are triggered by ri...
Wanderley de Souza,Emile S Barrias
Wanderley de Souza
Extracellular vesicles (EVs) are released by virtually all cells in normal and in pathological conditions. They exhibit diverse sizes, contents, and surface markers. These vesicles transport cellular components such as proteins, mRNAs, miRN...
Archaeal Diversity Sheds New Light on the Origin of the Eukaryotic Endomembrane System [0.03%]
考古多样性揭露真核细胞内膜系统起源的新线索
Zhongyi Lu,Siyu Zhang,Ning Song et al.
Zhongyi Lu et al.
The emergence of the endomembrane system marks a pivotal milestone in eukaryogenesis, transforming a primitive prokaryotic cell into a highly intracellular, compartmentalized eukaryotic cell. The molecular machinery underlying the endomembr...
Forming Strong Bonds: Building Microbial Surface Structures by Donor-Strand Exchange [0.03%]
强结伴：供体寡核苷酸交换构建微生物表面结构
Karla Cardenas Arevalo,David G Thanassi
Karla Cardenas Arevalo
Microbial organisms assemble a diverse array of surface structures to facilitate critical functions including motility, adhesion, and biofilm formation. As extracellular organelles, pili and related surface structures must be able to functi...
Jill G Canestrari,Todd A Gray
Jill G Canestrari
The focal site of ribosome assembly and maturation in bacteria is the 5' untranslated region (UTR). Leaderless messenger RNAs (mRNAs) lack a 5' UTR and therefore present a conundrum for translation initiation. Leaderless mRNAs in Escherichi...
Maia V Palka,Brian S Leander
Maia V Palka
Cellular weaponry includes a diverse array of ballistic structures, generally referred to as extrusomes, found across the tree of life. Extrusomes have evolved multiple times independently; are morphologically diverse, including structures ...