Introduction [0.03%]
绪论
Susan Gottesman
Susan Gottesman
Decoding Microbial Community Assembly: Insights on Vectors of Infectious Diseases [0.03%]
解读微生物群落汇编：传染病载体的新见解
Dasiel Obregon,Apolline Maitre,Elianne Piloto-Sardiñas et al.
Dasiel Obregon et al.
Vector-borne diseases (VBDs), which are caused by pathogens transmitted by vectors such as mosquitoes and ticks, account for more than 17% of infectious diseases and more than 700,000 deaths annually. The complexity of VBDs arises from ecol...
Mukhtar Sadykov,Filipa Rijo-Ferreira
Mukhtar Sadykov
Circadian rhythms play a fundamental role in regulating biological processes across the tree of life. While these 24-h cycles are well-characterized in model organisms, their role in parasitic organisms has remained largely unexplored until...
Mark A Hanson,Hannah E Westlake,Philippe Bulet et al.
Mark A Hanson et al.
Drosophila fruit flies are a powerful model for studying innate immunity. In Drosophila, seven classical antimicrobial peptide (AMP) gene families were identified in the 1990s. These genes are primarily regulated by the TOLL and IMD NF-κB ...
Pathogenic Fungal Sensing and Responses to Stressful Host Environments [0.03%]
致病真菌对不利宿主环境的感应与应答机制研究进展
Jackson R Rapala,Faith Anderson Davis,Ajay Larkin et al.
Jackson R Rapala et al.
Despite the ubiquity of fungi in nature, only a small fraction are pathogenic to humans, and the majority of these fungi are opportunistic and affect immunocompromised individuals. In general, pathogen emergence is restricted by the ability...
Samuel T E Greenrod,Tobias E Hector,Michael Blazanin et al.
Samuel T E Greenrod et al.
Bacteriophages (phages) are virtually ubiquitous and play a fundamental role in the ecological and evolutionary dynamics of their bacterial hosts. While phages are found across many thermal environments, they can be highly sensitive to chan...
Crista B Wadsworth,Maira Goytia,William M Shafer
Crista B Wadsworth
Alongside the crisis of antimicrobial-resistant gonorrhea is the threat of bystander selection on commensal Neisseria. As Neisseria species are permissive to gene flow across lineages, their evolutionary fates are irrevocably intertwined. H...
A Comparative Analysis: Molecular Mechanisms of Carbon Catabolite Repression in Bacteria [0.03%]
碳代谢调控的分子机制及其在细菌中的保守性和多样性
Elisabeth Sonnleitner
Elisabeth Sonnleitner
In the environment, bacteria often encounter a mixture of different carbon sources (C-sources) that can potentially be used. However, their uptake and utilization are selective and controlled in a hierarchical order by a complex regulatory ...
Marina Elez,Chiara Enrico Bena,Lydia Robert
Marina Elez
All genetic variation fueling evolution depends on mutations. Although mutations have been extensively studied for almost a century, until a decade ago the investigation of mutations was limited to population-level analysis. This constraint...
Why Do Filamentous Actinomycetota Produce Such a Vast Array of Specialized Metabolites? [0.03%]
丝状放线菌为什么会产生如此众多的专业代谢产物？
Luis M Cantu Morin,Kilian Dekoninck,Varun Sridhar et al.
Luis M Cantu Morin et al.
Bacteria of the phylum Actinomycetota are extremely diverse: They inhabit niches ranging from soils and ocean sediments to the normal human microbiota, and they cause tuberculosis, one of the most prevalent chronic bacterial infections. The...