Marina Elez,Chiara Enrico Bena,Lydia Robert
Marina Elez
All genetic variation fueling evolution depends on mutations. Although mutations have been extensively studied for almost a century, until a decade ago the investigation of mutations was limited to population-level analysis. This constraint...
Why Do Filamentous Actinomycetota Produce Such a Vast Array of Specialized Metabolites? [0.03%]
丝状放线菌为什么会产生如此众多的专业代谢产物？
Luis M Cantu Morin,Kilian Dekoninck,Varun Sridhar et al.
Luis M Cantu Morin et al.
Bacteria of the phylum Actinomycetota are extremely diverse: They inhabit niches ranging from soils and ocean sediments to the normal human microbiota, and they cause tuberculosis, one of the most prevalent chronic bacterial infections. The...
Devaki Bhaya,Gabriel Birzu,Eduardo P C Rocha
Devaki Bhaya
Cyanobacteria played a pivotal role in shaping Earth's early history and today are key players in many ecosystems. As versatile and ubiquitous phototrophs, they are used as models for oxygenic photosynthesis, nitrogen fixation, circadian rh...
Alex Graça Contato,Thiago Machado Pasin,Maria de Lourdes Teixeira de Moraes Polizeli
Alex Graça Contato
Plant biomass has emerged as a cornerstone of the global bioenergy landscape because of its abundance and cost-effectiveness. The cell wall of plant biomass is an intricate network of cellulose, hemicellulose, and lignin. The hydrolysis of ...
Making Fungal-Photobiont Symbioses in the Lab: Past, Present, and Future of the Elusive In Vitro Lichen [0.03%]
揭秘菌光互生的实验室构建：地衣离体培养的过去、现在与未来
Arseniy Belosokhov,Toby Spribille
Arseniy Belosokhov
The ability to synthesize lichen symbioses in vitro from pure cultures of transformable symbionts would be a game changer for experiments to identify the metabolic interplay that underpins the success of lichens. However, despite multiple r...
Qiong Li,Feng Yang,Cong-Zhao Zhou
Qiong Li
Prevalent in marine and freshwater ecosystems, cyanophages compose a class of double-stranded DNA viruses that specifically infect cyanobacteria. During billions of years of coevolution, cyanophages and cyanobacteria have significantly cont...
Heather L Emery,Robert L Kerby,Federico E Rey
Heather L Emery
Purines are ubiquitous metabolites that play evolutionarily conserved roles, including as precursors to molecules central to life. Purine synthesis is metabolically and energetically expensive; thus, under physiological conditions, intermed...
Malcolm J McConville,Eleanor C Saunders,Julie E Ralton
Malcolm J McConville
Apicomplexan and trypanosomatid parasites cause important human diseases, including malaria, toxoplasmosis, Chagas disease, and human leishmaniasis. The mammalian-infective stages of these parasites colonize nutrient-rich, intracellular nic...
Non-Conventional Yeasts as a Source of Genetic Diversity and Biotechnological Potential [0.03%]
非常规酵母的遗传多样性和生物技术潜力来源
Pablo Villarreal,Jennifer Molinet,Stephanie Braun-Galleani et al.
Pablo Villarreal et al.
Most of our current knowledge about yeast is based on the workhorse Saccharomyces cerevisiae. However, can this yeast represent the vast array of natural yeast life-forms? This review discusses significant recent advances in the study of no...
Mingxu Fang,Carrie L Partch,Andy LiWang et al.
Mingxu Fang et al.
Circadian clocks are biological timekeeping mechanisms that synchronize physiology with the 24-h day-night cycle and provide temporal order to cellular events that recur daily as circadian rhythms. The cyanobacterium Synechococcus elongatus...